For evaluation of the colon, Colonoscopy is the current standard method. Diagnostic accuracy and therapeutic safety of colonoscopy depends on the quality of the colonic cleansing or preparation. The ideal preparation for colonoscopy would reliably empty the colon of all fecal material in a rapid fashion with no gross or histologic alteration of the colonic mucosa. The preparation would also not...

Colonoscopy is widely used for the diagnosis and treatlesions that are endoscopically subtle or difficult to rement of colon disorders. Properly performed, colonoscopy is generally safe, accurate, and well-tolerated. Visualization of the mucosa of the entire large intestine and distal terminal ileum usually is possible during colonoscopy. Polyps can be removed during colonoscopy, thereby reduci...

Adequate bowel preparation is essential before a colonoscopy, allowing us to make a proper examination of the entire mucosa. The ideal method of colon cleansing should be fast, safe, and get a proper cleaning with minimal discomfort for the patient. Today we have a wide variety of colon cleansing products, information sometimes becomes confused. A good colon preparation depends partly on correc...

References 1. Scabini S, Rimini E, Romairone E, Scordamaglia R, Damiani G, Pertile D, Ferrando V: Colon and rectal surgery for cancer without mechanical bowel preparation. One Center Randomized Prospective Trial 2010, 8:35. 2. Zmora O, Mahajna A, Bar-Zakai B, Rosin D, Hershko D, Shabtai M, Krausz M, Ayalon A: Colon and Rectal Surgery Without Mechanical Bowel Preparation. A Randomized Prospectiv...

Background Colonoscopy is the gold standard investigation for assessing of the intra-luminal colorectal pathology. Effective bowel preparation contributed efficient visualizing of the colon. Osmotic laxatives such as sodium phosphate (NaP) are commonly used for colonic preparation for colonoscopy. A meta-analysis suggested that NaP offered a more effective and more readily completed preparation...

Colon capsule endoscopy utilizing PillCam COLON 2 capsule allows for visualization potentially of the entire colon and is currently approved for patients who cannot withstand the rigors of traditional optical colonoscopy (OC) and associated sedation as well as those that had an OC that was incomplete for technical reasons other than a poor preparation. We will then describe the prior experience...

Preparation of Calcium Alginate-Tetrandrine Beads Using Ionic Gelation Method as Colon-Targeted Dosage FormRaditya Iswandana, Kurnia Sari Setio Putri, Fitri Rina Wulandari, Ghaathy Najuda, Santi Purna Sari, Joshita Djajadisastra

BACKGROUND Sodium phosphate (NaP) is a low-volume, hyperosmolar laxative that is an effective bowel-cleansing agent in humans. HYPOTHESIS NaP will be as safe and efficacious as polyethylene glycol (PEG) bowel preparation for colonoscopy in dogs. ANIMALS Eight purpose-bred healthy dogs. METHODS In phase I, standard (NaP and enemas; NaP(1)) and control preparations (PEG and enemas) were com...