نتایج جستجو برای: colon targeting

تعداد نتایج: 220204  

2017
Jaeil Kim Eun-ju Do Helen Moinova Sang Mun Bae Ja Young Kang Seung-Mo Hong Stephen P. Fink Jinmyoung Joo Young-Ah Suh Se Jin Jang Sung Wook Hwang Sang Hyoung Park Dong-Hoon Yang Byong Duk Ye Jeong-Sik Byeon Jaewon Choe Suk-Kyun Yang Sanford D. Markowitz Sang-Yeob Kim Seung-Jae Myung

A versatile biomarker for detecting colonic adenoma and colon cancer has yet to be developed. Colon cancer secreted protein-2 (CCSP-2) is a protein specifically expressed and secreted in colon adenomas and cancers. We developed a fluorescent imaging method based on CCSP-2 targeting for a more sensitive and specific detection of colorectal tumors. CCSP-2 expression was evaluated in human colon a...

Journal: :Journal of Pharmaceutical Negative Results 2022

Research on colon-targeted polymers delivery systems is ongoing for conditions such ulcerative colitis, Crohn's disease, colon cancer, as well the of peptide or protein medications and vaccines. For colon-specific disorders in particular, focused nano-drug to helpful because nanoparticles can build up sick areas, improve therapeutic efficacies, allow localized therapies, which lower systemic to...

Journal: :Advanced Research in Gastroenterology & Hepatology 2018

2009
Tiwari Akanksha Shukla Raj Kumar

Although oral delivery has become a widely accepted route of administration of therapeutic drugs, the gastrointestinal tract presents several formidable barriers to drug delivery. Colonic drug delivery has gained increased importance not just for the delivery of the drugs for the treatment of local diseases associated with the colon but also for its potential for the delivery of proteins and th...

2014
Susan Hua

Colon targeted drug delivery is an active area of research for diseases affecting the colon, as it shows promise in improving the efficacy of therapeutics and reducing systemic toxicity. Improved oral drug delivery design has unequivocally improved the bioavailability of drugs to the colon. The oral route of administration is the most common method of drug delivery. It is the preferred route of...

Journal: :International Journal of Applied Pharmaceutics 2017

Journal: :Current Colorectal Cancer Reports 2009

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