common variable immunodeficiency (cvid) and selective iga deficiency (sigad) are the most common primary antibody deficiencies. these two diseases may have coincidence in one family and sigad can progress to cvid which suggest common underlying genetic defects between sigad and cvid. this study was designed to find the prevalence of multiple cases in families of iranian patients with cvid or si...

Variable elimination (VE), a central component of Bayesian network inference, starts and ends with clear structure and semantics, yet all intermediate distributions, whether normalized or unnormalized, are denoted as potentials. In this paper, a condition is given stating when intermediate distributions are defined with respect to the joint distribution. Theoretical and practical advantages of ...

Instrumental variable (IV) estimation typically requires the user to correctly specify the relationship between the regressors and the outcome to obtain a consistent estimate of the effects of the treatments. This paper proposes doubly robust IV regression estimators that only require the user to either correctly specify the relationship between the measured confounding variables (i.e., include...

Etiologies for human hypogammaglobulinemias are diverse and include genetic and nongenetic causes. Although recent reviews focus on the complex genetics of common variable immunodeficiency, in this review, we survey different causes of hypogammaglobulinemias and discuss possible mechanisms.

In the next decennia, upscaling even towards 10 MW wind turbines may be necessary to lower the costs of offshore wind energy. This requires considerable reductions of turbine loads. Variable speed turbines with active pitch control are most favorable and prevailing nowadays. Currently, the turbine blades are turned collectively to limit the excess of wind power and to regulate the rotor speed a...

Studies of downtrend have reported that accents/tones are realised at progressively lower F0 values during an utterance. Listeners are reported to compensate for such F0 variations over time( Pierrehumbert 1979). Underlying the downtrend studies is the assumption that the phonological categories under investigation are invariant over time and that declination can be factored out of the quantita...

Bistable N-H···N hydrogen bonds between rotors and stators enable delicate modulation of dynamic molecular motion by slowing down the fast rotation in a N-H···N hydrogen-bonded organic co-crystal of 1,2-diazabicyclo(2.2.2)octane bis(thiourea), which has been elucidated by the combination of variable-temperature (VT) X-ray structure analyses and VT solid-state nuclear magnetic resonance techniques.