A 61-year-old patient underwent endoscopic exploration for anemic syndrome. His medical history revealed that he had been taking a drug based on a mixture of medicinal herbs as laxative for nine years. This product consists of anthranoid-containing laxatives as aloe, senna, rhubarb, cascara and frangula. Endoscopy revealed diffuse dark brown pigmentation throughout his colon, which is compatibl...

Neurocutaneous melanosis (NCM) is a rare congenital disease that is characterized by the presence of large or multiple congenital melanocytic nevi and melanotic lesions of the central nervous system. We report here on the CT and MR imaging findings of an unusual case of NCM that was associated with intraventricular dermoid and Dandy-Walker malformation.

The gross and microscopic features of an unusual case of neurocutaneous melanosis are described. This is an example of the rare association between a primary central nervous system malignant melanoma and a giant congenital melanocytic naevus of 'bathing trunk' distribution.

Neurocutaneous melanosis is a rare congenital syndrome characterized by large or multiple congenital melanocytic nevi and benign or malignant pigment cell tumors of the leptomeninges. The prognosis is extremely poor for symptomatic patients, even in the absence of malignant melanoma. We present serial MR imaging findings in the brain and spine of a child with congenital giant hairy nevi who dev...

Cellular blue nevus is an uncommon pigmented tumor in the conjunctiva, where it generally appears as a deep, circumscribed, pigmented conjunctival mass. We report a case of conjunctival blue nevus that clinically resembled primary acquired melanosis and gave rise to conjunctival melanoma. A 41-year-old man developed a diffuse pigmented mass in the inferior fornix of his left eye. Over a 20-year...

780 Ann Dermatol Received December 10, 2014, Revised February 7, 2015, Accepted for publication February 18, 2015 Corresponding author: Joanna Mangana, Department of Dermatology, University Hospital Zurich, Gloriastrasse 31, CH 8091, Zurich, Switzerland. Tel: 41-44-255-3155, Fax: 41-44-255-454, E-mail: johanna. mangana@ usz.ch This is an Open Access article distributed under the terms of the Cr...