BACKGROUND Aphakic glaucoma is a common complication after congenital cataract extraction, especially in those who have surgery during infancy. This case report describes a case of bilateral pupillary block glaucoma diagnosed with intraoperative ultrasound biomicroscopy (UBM) after removal of congenital cataract. CASE PRESENTATION We present a case report of a 9-month-old infant with bilatera...

BACKGROUND It is well-known that lensectomy surgery during the first year of life increases one's risk of aphakic glaucoma. However, it is controversial whether there is a specific time period during the first year of life after which performing lensectomy surgery has a lower risk of aphakic glaucoma development. PATIENTS AND METHODS A retrospective chart review was performed of all patients ...

The reported success rates in the treatment of congenital glaucoma with goniotomy, trabeculotomy, and trabeculectomy suggest that trabeculectomy should be performed if the other procedures fail. We propose that the decision to perform primary trabeculectomy in primary and secondary congenital glaucoma reduces the effect which the many variable findings in surgical anatomy may have on the outcom...

PURPOSE To clinically and genetically characterize a distinct phenotype of congenital megalocornea (horizontal corneal diameter ≥13 mm) with secondary glaucoma from spherophakia and/or ectopia lentis during childhood in affected Saudi families. METHODS Clinical exam, homozygosity scan, and candidate gene analysis. RESULTS From 2005 to 2010, eight affected individuals from three consanguineo...

Noteworthy heterogeneity exists in the rare diseases associated with childhood glaucoma. Primary congenital glaucoma is mostly sporadic; however, 10% to 40% of cases are familial. CYP1B1 gene mutations seem to account for 87% of familial cases and 27% of sporadic cases. Childhood glaucoma is classified in primary and secondary congenital glaucoma, further divided as glaucoma arising in dysgenes...

Congenital syphilis is caused by Treponema pallidum infection through the placenta in the embryonic stage and causes ophthalmic symptoms in childhood and adulthood. Ocular involvement of congenital syphilis consists of interstitial keratitis, anterior uveitis, acute iridocyclitis, chorioretinitis, perivasculitis, optic neuritis and secondary glaucoma. Interstitial keratitis and anterior uveitis...

Objective To investigate the causes of secondary glaucoma in retinoblastoma (RB) and underscore the significance of glaucoma as a presenting sign of RB. Methods A 7-month-old boy, initially diagnosed with congenital glaucoma in the left eye (OS), revealed an intraocular RB on further work-up. The eye was eventually enucleated and histopathology showed iris neovascularization (NVI) and a large s...

PURPOSE Few studies have provided epidemiological characteristics of childhood glaucoma in a large, multiethnic population. This information is important if we are to better screen for and characterize this specific type of glaucoma. In this study, we evaluate the characteristics of patients with childhood glaucoma, including glaucoma suspects, as identified through the Dallas Glaucoma Registry...

Glaucoma is a leading cause of irreversible blindness in Canada. Congenital glaucoma usually manifests during the first years of life and is characterised by severe visual loss and autosomal recessive inheritance. Two disease loci, on chromosomes 1p36 and 2p21, have been associated with various forms of congenital glaucoma. A branch of a large six generation family from a consanguineous Amish c...