: One of the most prevalent congenital deformities in infants is heart disease (CHD) that has high rates morbidity and mortality. To enhance patient clinical outcomes, it vital to investigate CHD pathophysiology. Cardiovascular illness been linked TGF-1 signaling disruptions.

In recent decades a majority of neonatal deaths, chronic medical conditions and disabilities are found to be associated with the congenital defects. Congenital defects are the structural and functional malformations in babies present at the birth. These defects can cause reduced survival rates of affected individuals and considerable percentage of neonatal death worldwide. In this study an exte...

BACKGROUND Little is known of the optimal dose and administration schedule of hydrocortisone in critically ill patients with congenital adrenal hyperplasia (CAH) caused by 21-hydroxylase deficiency. AIM To determine plasma cortisol concentrations after intravenous administration of hydrocortisone in children with CAH and to relate these to plasma cortisol concentrations achieved by endogenous...

BACKGROUND Data on congenital anomalies from developing countries of the sub-Saharan region are scarce. However, it is important to have comprehensive and reliable data on the description and prevalence of congenital anomalies to allow surveillance and the implementation of appropriate public health strategies for prevention and management. In this study, we describe the profile of congenital a...

Toxoplasma gondii is a leading cause of severe foodborne illness in the United States. Population-based studies have found T. gondii infection to be more prevalent in racial/ethnic minority and socioeconomically disadvantaged groups. Soil contaminated with cat feces, undercooked meat, and congenital transmission are the principal sources of infection. Toxoplasmosis-associated illnesses include ...