to malignant melanoma. The exact cause is unknown. There may be hereditary factors, autosomal dominance or other multifactor determinants. Management depends upon size, location and malignant transformation. Surgical excision is the mainstay of treatment. Cultured epidermal autograph has been used successfully to cover postoperative large surface area defect. We report a one-day-old male child ...

Becker's nevus, also called Becker's melanosis or pigmented hairy epidermal nevus, is a benign cutaneous hamartoma characterized by hyperpigmented macule usually with hypertrichosis. It is rarely associated with neurofibromatosis. We report a 2 1⁄2 yrs old male child with coexistent congenital Becker’s nevus and type 1 neurofibromatosis.

Nevus depigmentosus is a stable and well-circumscribed congenital hypomelanosis that may be in an isolated, dermatomal or systemic form. An 18-yr-old Korean man with segmental nevus depigmentosus developed multiple pigmented nevi which were present only within the confines of the leukoderma. Histologic and electron microscopic studies rendered a diagnosis of nevus depigmentosus with dysplastic ...

Syringocystadenoma papilliferum is an uncommon benign apocrine gland tumour, mostly of congenital or early childhood onset, affecting head and neck. In addition, nevus sebaceous is commonly associated with this tumor. Here, we document three cases of syringocystadenoma papilliferum with many atypical features, such as the involvement of rare sites (abdomen, axilla and thigh), absence of nevus s...

Phacomatosis pigmentovascularis is a rare, congenital condition characterized by a combination of cutaneous melanocytic lesions and vascular malformation. We discuss an entirely unique case of Phacomatosis pigmentovascularis with nevus of Ota, extensive Mongolian spot, nevus flammeus, nevus anemicus and cutis marmorata telangiectatica congenita, which may represent a heretofore undescribed vari...

BACKGROUND Deep penetrating nevus (DPN) is a distinct variant of melanocytic nevus and remains a histopathologic challenge to pathologists because of its resemblance to blue nevus, malignant melanoma, pigmented Spitz nevus, and congenital melanocytic nevus. It often goes unrecognized due to its relative rarity. CASE PRESENTATION Here we report a case of DPN of the left anterior leg in a 51-ye...

During the normal development of skin, pluripotential cells give rise to keratinocytes, sebaceus glands, hair follicles, apocrine glands and eccrine glands. A hamartoma, or an abnormal mixture of a tissue’s normal components, results from an error in development, among which some show malignant potential. We report two Chinese cases of giant congenital cutaneous hamartoma, a nevus sebaceus of J...

Congenital melanocytic nevus consists of congregations of nevomelanocytes. It is found in approximately 1% of new born infants. Congenital melanocytic nevus needs to be excised before it transforms into a malignant lesion. Many strategies have been attempted for the removal and reconstruction of the nevus. Serial excision enables wound closure to be accomplished with a shorter scar than if the ...

Lentigines are usually flat, pigmented macules on the skin and mucosa. These lesions are characterized by mostly smaller than 0.5 cm, irregular borders and different shades of brown and black. They can be in the form of circumscribed or widespread lesions, and occur either as isolated lesion or as a part of some congenital syndromes. The speckled lentiginous nevus is also named as Nevus Spilus ...

INTRODUCTION A congenital lower lip nevus is common, but a lower lip length lesion of more than 40% is hard to excise simply, without any distortion. We designed a lower lip bilateral advanced skin flap to restore the wound surface after completely and successfully removing the nevus. CASE PRESENTATION A 13-year-old Mongolian girl was referred to us with a giant congenital lower lip nevus. Th...