PURPOSE To analyze the expression of apoptosis and cell proliferation molecules in pterygium tissues of Chinese patients. METHODS Thirty-three pterygia were surgically removed using the bare sclera procedure, and 23 normal bulbar conjunctivas were also obtained. Formalin-fixed, paraffin-wax-embedded tissues were analyzed by immunohistochemistry with anti- proliferating cell nuclear antigen (P...

AIM To examine the expression of αB-crystallin and vascular endothelial growth factor (VEGF) in conjunctival squamous cell carcinoma (CSCC). MATERIALS AND METHODS Seven CSCCs and three normal conjunctivas that were surgically excised were studied. Paraformaldehyde-fixed, paraffin-embedded tissue sections were processed for immunohistochemistry with antibodies against αB-crystallin, its phosph...

AIMS To analyse age-related changes of human conjunctiva by in vivo laser scanning confocal microscopy (LSCM). METHODS 80 healthy subjects were enrolled and divided into four groups according to age: A (0-19 years), B (20-39 years), C (40-59 years) and D (over 60 years). In vivo LSCM was performed on the subjects' bulbar conjunctivas, and the images were recorded. The morphology and densities...

Macrophages infiltrate the conjunctiva in severe cases of allergic conjunctivitis (AC) such as atopic keratoconjunctivitis (AKC). We established experimental immune-mediated blepharoconjunctivitis (EC) in Brown Norway (BN) rats as a model for severe types of AC. We investigated whether macrophage infiltration in the conjunctiva in this EC model is inhibited by clodronate liposomes (CL2MDP-lip)....

A patient with severe toxic epidermal necrolysis underwent 2 cycles of therapeutic plasma exchange and received specialized wound care for widespread skin damage of more than 80% of his body surface area. Extensive involvement of mucous membranes, including the conjunctivas and the oropharyngeal cavity, and damage of his genitourinary organs required meticulous wound care. Daily care of injurie...

Brucellosis, is a systemic infection disease that is caused by Brucella bacteries. Bacteries cause infection by ingestion of unsterilized milk or meat of infected animals, close contact with their secretions, inhalation of infected aerosol or inoculation to conjunctivas (1, 2). A genus of Gram-negative bacteria, non-motile, non-encapsulated coccobacilli brucella bacteries causes symptoms 1-3 we...

Railivay Hospital, Hubli, M. and S. M. Railway. Th? following cases of relapsing fever were admitted to this hospital during a local epidemic in August to October 1923. Some of them might have been mistaken for plague, had not the diagnosis been confirmed in each instance by the finding of spirochetes in blood films:? Case 1, aet. 27.?Admitted to hospital for continuous fever for 6 days, slight...

PURPOSE The pterygium is characterized by a fibrovascular neoformation from the bulbar conjunctiva into the cornea. The recent discovery that abnormal markers associated with tumor diseases are identified in the pterygium strengthens the theory that the pterygium is a tumor-like disease rather than a degenerative disease. The CD30 molecule has been identified in neoplastic and normal epithelial...

PURPOSE Secretory IgA (SIgA) is a critical local defense mechanism of mucosal immunity. Although the conjunctiva, as part of the ocular surface, has a mucosa-associated lymphoid tissue, the production of SIgA by local plasma cells and its transport is unequivocally accepted to occur only in the upstream lacrimal gland (LG). The molecular components were therefore investigated by immunohistochem...