The level of glycaemic control necessary to achieve optimal short-term and long-term outcomes in subjects with type 1 diabetes mellitus (T1DM) typically requires intensified insulin therapy using multiple daily injections or continuous subcutaneous insulin infusion. For continuous subcutaneous insulin infusion, the insulins of choice are the rapid-acting insulin analogues, insulin aspart, insul...

since there is no detailed hospital based incident reporting system, this study was designed to evaluate the medication errors associated with infusion pumps in intensive care unit (icu). the investigation was conducted in a teaching hospital in the form of a prospective, observational study. a sample size of 43 doses administered to icu patients was chosen to enable reliable estimate of error ...

A young woman with no history of diabetes tried to commit suicide by injecting 2800 units of subcutaneous NPH insulin. She was transferred to Loghman Hospital within 12 hours. The main clinical symptom was continuous seizure activity which was resistant to all forms of routine drug therapy. The patient was treated with intravenous hypertonic glucose (50%) followed by continuous glucose (10...

a young woman with no history of diabetes tried to commit suicide by injecting 2800 units of subcutaneous nph insulin. she was transferred to loghman hospital within 12 hours. the main clinical symptom was continuous seizure activity which was resistant to all forms of routine drug therapy. the patient was treated with intravenous hypertonic glucose (50%) followed by continuous glucose (10%) in...

To investigate the quality of glycaemic control that is achievable in diabetic patients with persistent proteinuria and asymptomatic but declining renal function three matched groups of patients were studied. The first comprised diabetics with proteinuria receiving continuous subcutaneous insulin infusion; the second, diabetics without proteinuria receiving continuous subcutaneous insulin infus...

OBJECTIVE To compare glycaemic control and insulin dosage in people with type 1 diabetes treated by continuous subcutaneous insulin infusion (insulin infusion pump therapy) or optimised insulin injections. DESIGN Meta-analysis of 12 randomised controlled trials. PARTICIPANTS 301 people with type 1 diabetes allocated to insulin infusion and 299 allocated to insulin injections for between 2.5...