Objective: In this study, the zeolite-coated iron oxide nanoparticles were evaluated as MRI contrast agent and effect of the nanocomposite synthesis method on MRI contrast was tested. Materials and Methods: Ion exchange method was used for synthesis of iron oxide-zeolite and the as prepared nanocomposite was characterized by XRD, FESEM and TEM. The nanocomposite toxicity in the cell culture, a...

background :inversion recovery (ir) pulse sequences can generate t1-weighted images with a different range of inversion time (ti) to suppress or null the signal intensity (si) for a specified tissue. in this study, we aimed to investigate the effect of ti values on the concentration of the contrast agent, which leads to a minimum signal intensity, using an inversion recovery t1-weighted 3-dimen...

Objective(s): The aim of this work was to prepare and characterize magnetic nanoparticles (MNPs) as theranostic system to act simultaneously as drug carrier and MRI contrast agent. Chitosan-coated MNPs (CMNPs) were prepared and loaded with silymarin. Silymarin-loaded CMNPs were characterized with various techniques and their potential as MRI contrast agent was also evaluated. Materials and Meth...

background:  nowadays mri examinations have been widely used in clinical applications for many diagnoses. the use of contrast agent in mri improves lesion detection and characterization and causes more accurate diagnosis.  objectives: the aim of this study was comparing to optimal dose of magnevist contrast agent in modified t1w se (spin echo), t1w fse (fast spin echo) and t1w gre (gradient ech...