ACE inhibitors have achieved widespread usage in the treatment of cardiovascular and renal disease. ACE inhibitors alter the balance between the vasoconstrictive, salt-retentive, and hypertrophic properties of angiotensin II (Ang II) and the vasodilatory and natriuretic properties of bradykinin and alter the metabolism of a number of other vasoactive substances. ACE inhibitors differ in the che...

results the ace inhibitory activities of hydroalcoholic extracts were as follows; m. vulgare > n. jatamansi > p. ferulacea. the least ic50 value was related to the hydroalcoholic extract of m. vulgare (0.791 mg/ml). the ic50 values of n. jatamansi and p. ferulacea were 2.147 and 4.057 mg/ml, respectively. conclusions the results supported the traditional antihypertensive use of these plants, es...