BACKGROUND The CD38/cyclic ADP-ribose (cADPR) pathway plays a role in various central nervous system diseases and in morphine tolerance, but its role in local anesthetic intoxication is unknown. The aim of this study was to determine the role of the CD38/cADPR pathway in ropivacaine-induced convulsion. METHODS Forty male Sprague-Dawley rats were randomly divided into five groups (n = 8 per gr...

Records of 199 children aged 5 to 71 months (mean 22.8) admitted after febrile convulsion were examined. Although 32 had recurrent convulsions (some before admission) none suffered a convulsion more than 24 hours after hospital admission.

PURPOSE The possibility that hyperammonemia may be associated with generalized convulsion (GC) was retrospectively investigated. METHODS Subjects comprised 17 patients with GC who were transported to our department and underwent analysis of serum biochemistry, including ammonia, since October 2004. RESULTS Causes of convulsion included intracranial lesions (n=8), endocrine diseases (n=2), e...

OBJECTIVE The relationship between iron deficiency anemia and febrile convulsions has been examined in several studies with conflicting results. The authors aimed to evaluate the relation, if any, of iron status with first febrile convulsion. METHODS In this case-control study, the authors assessed 200 children with a diagnosis of first febrile convulsion, aged between 6 months and 5 years, d...

Objectives: In this study, in order to review the semiology of traditional medicine and apply it to current medical terminology, traditional and classic medicine resources on the subject of convulsion were reviewed. The connotative meaning of the term “convulsion” in traditional medicine is “the twitch of a non-specific part of the body, prepared for an expansive movement in a consistent, rapid...

Febrile convulsions are a common form of childhood seizure. It is estimated that between 2 and 5% of children will have a febrile convulsion before the age of 5. It has long been recognized that there is a significant genetic component for susceptibility to this type of seizure. Wallace, Berkovic and co-workers recently reported linkage of a putative autosomal dominant febrile convulsion gene t...

BACKGROUND Febrile convulsion in children is a frightening experience for the mothers. This experience may have unknown aspects, which must be investigated in order to plan better support for the mothers and children. This study is conducted with the aim of exploring the experiences of mothers whose children suffer from febrile convulsion. METHODS This study was based on a qualitative content...