Although carbon monoxide (CO) has traditionally been viewed as a toxic gas, increasing evidence suggests that it plays an important homeostatic and cytoprotective role. Its therapeutic use, however, is limited by the side effects associated with CO inhalation. Recently, transition metal carbonyls have been shown to be a safe and effective means of transporting and releasing CO groups in vivo. T...

OBJECTIVE We compared the antithrombotic effects in vivo of 2 chemically different carbon monoxide-releasing molecules (CORM-A1 and CORM-3) on arterial and venous thrombus formation and on hemostatic parameters such as platelet activation, coagulation, and fibrinolysis. The hypotensive response to CORMs and their effects on whole blood gas analysis and blood cell count were also examined. MET...

Little is known about how production practices influence taro (Colocasia esculenta) corm density. This study was conducted to determine the effects soil type and harvest age have on corm density. Niue taro variety was grown on 3 soil types on Tutuila, American Samoa, and harvested 6, 7, 8, and 9 months after planting. Corm densities were measured using a double-weighing method: weighting the co...

Carbon monoxide (CO)-releasing molecules (CO-RMs) are intensively studied to provide cytoprotective and anti-inflammatory effects of CO in inflammatory conditions including intestinal inflammation. The water-soluble CORM-A1 reduced apoptosis and NADPH oxidase (NOX)-derived reactive oxygen species (ROS) induced by tumor necrosis factor (TNF)-α/cycloheximide (CHX) in mouse MODE-K intestinal epith...

Carbon monoxide, which is generated in mammals during the degradation of heme by the enzyme heme oxygenase, is an important signaling mediator. Transition metal carbonyls have been recently shown to function as carbon monoxide-releasing molecules (CO-RMs) and to elicit distinct pharmacological activities in biological systems. In the present study, we report that a water-soluble form of CO-RM p...

Background & Aim: Saffron (Crocus sativus L.) formerly was important in Turkey. Saffron cultivation has been decreased and it is now only cultivated in three villages in this country. It is triploid and exclusively propagated in a vegetative way by corms. In Turkey, saffron is traditionally planted by placing corms in rows randomly without grading or sorting; which results in placement...

background & aim: saffron (crocus sativus l.) formerly was important in turkey. saffron cultivation has been decreased and it is now only cultivated in three villages in this country. it is triploid and exclusively propagated in a vegetative way by corms. in turkey, saffron is traditionally planted by placing corms in rows randomly without grading or sorting; which results in placement of c...