purpose: to assess the short-term effect of mitomycin-c (mmc) 0.02% on endothelial cell density and morphology after photorefractive keratectomy (prk) in patients with moderate myopia. methods: forty-two eyes of 21 participants with moderate myopia (range, -4.0 to -8.0 d) underwent prk with mmc 0.02% for 40 seconds. specular microscopy was performed preoperatively and repeated 6 months after su...

Aim: This study focused on exploring the effects of refractive error and its association with various corneal parameters such as curvature (CC), thickness (CT), endothelial cell density (ECD), volume (CV) among young adults in Saudi Arabia.

AIM To investigate the corneal endothelial cell density and morphology and central corneal thickness in the Guangxi Maonan and Han adolescent students of China. METHODS Noncontact specular microscope (Topcon SP3000P, Tokyo, Japan) was performed in 133 adolescent students of Maonan nationality (M:F 54:79) and 105 adolescent students of Han nationality (M:F 50:55), 5 to 20y of age, who were ran...

purpose: to evaluate the adverse effects of intravitreal injection of sterile chloramphenicol eye drops on corneal endothelial cells of donated corneas. methods: 100 donor corneas were enrolled in the study. one eye of each donor underwent intravitreal injection of sterile chloramphenicol eye drops following vitreous tap and the fellow eyes were served as controls. after corneo-scleral excision...

Diabetic keratopathy is an ocular complication that occurs with diabetes. In the present study, the effect of diabetic keratopathy on corneal optical density, central corneal thickness, and corneal endothelial cell count was investigated. One hundred and eighty diabetic patients (360 eyes) were enrolled in the study during the period from March, 2012 to March, 2013. The patients were divided in...

BACKGROUND/AIMS Deturgescence of the corneal stroma is controlled by the pumping action of the endothelial layer and can be monitored by measurement of central corneal thickness (pachymetry). Loss or damage of endothelial cells leads to an increase in corneal thickness, which may ultimately induce corneal decompensation and loss of vision. Little is known about the effect of moderate reductions...

Functional impairment of the human corneal endothelium can lead to corneal blindness. In order to meet the high demand for transplants with an appropriate human corneal endothelial cell density as a prerequisite for corneal function, several tissue engineering techniques have been developed to generate transplantable endothelial cell sheets. These approaches range from the use of natural membra...

AIM To compare corneal endothelial structure and central corneal thickness (CCT) between type II diabetics and non-diabetic control patients. To look for correlations between diabetic status and corneal findings. METHODS Hospital-based, observational study. 200 eyes (from 100 type II diabetic patients and 100 controls) were included. Specular microscopy and pachymetry were used to measure end...

PURPOSE To describe the differences of corneal endothelial cell densities, cell size variability and cell hexagonality in cataract populations of south Asia between sexes and ethnic groups. METHODS 1,235 eyes of 1,235 male and female patients 40-75 years of age with senile cataract were examined with non contact specular microscopy with semi-automated analysis technique. The cell data of the ...