In 14 subjects with normal coronary arteries the mean coronary sinus blood flow was 122 25 mI/min (range, 83 to 159 ml/min). The blood flow computed per 100 g of left ventricle was 82 + 16 ml/min, which is in the range of values obtained by nitrous oxide and coincidence counting methods. In 35 patients with arteriographically confirmed coronary artery disease the mean flow was similar (128 + 20...

The autoregulation of norepinephrine (NE) release mediated by presynaptic alpha and beta adrenoceptors on sympathetic nerve terminals in the heart of pentobarbital-anesthetized dog was studied. NE overflow elicited by left cardiac sympathetic nerve stimulation was determined from the coronary sinus blood, by using high-performance liquid chromatography with electrochemical detection. Intracoron...

Twenty-one patients with various heart diseases undergoing the coronary sinus catheterization had myocardial blood flow studies before and during isometric handgrip exercise. At 30% of the maximal voluntary contraction (MVC), handgrip increased both coronary sinus blood flow by 19.8% and myocardial O2 consumption by 21.0% on the average as compared to those at rest. At 20% of MVC, the increase ...

In 14 subjects with normal coronary arteries the mean coronary sinus blood flow was 122 25 mI/min (range, 83 to 159 ml/min). The blood flow computed per 100 g of left ventricle was 82 + 16 ml/min, which is in the range of values obtained by nitrous oxide and coincidence counting methods. In 35 patients with arteriographically confirmed coronary artery disease the mean flow was similar (128 + 20...

conclusions the coronary sinus flow per minute is the most accurate parameter among the three echocardiographic parameters mentioned above for the assessment of significant stenosis of the coronary artery. results flow (ml/minute), flow/lvm (ml/minuteg) and lv (d-s) mass a-l all correlated significantly with the percentage of stenosis (r = -0.64, p < 0.001; r = -0.47, p < 0.001; r = -0.56, p < ...

The changes in the coronary circulation, which are precipitated by the acute occlusion of the coronary sinus, have been investigated. In normal animals, retrograde blood emerging from the peripheral segment of a ligated and transected circumflex coronary artery is small in quantity, and arterial in nature, signifying an insignificant interarterial collateral flow. After the coronary sinus is ar...

AIMS To evaluate the correlation between the coronary sinus flow and the infusion volume in the coronaries and assess the performance of coronary sinus flow in predicting coronary artery occlusion in an isolated pig heart. MATERIAL AND METHODS The coronary sinus flow was measured in 16 isolated pig hearts by pulsed Doppler ultrasound. The correlation between the coronary sinus flow and the in...

The coronary haemodynamic effects of nifedipine and glyceryl trinitrate were compared in 22 patients undergoing investigations for suspected coronary artery disease. Myocardial blood flow was estimated by the coronary sinus thermodilution technique. In sinus rhythm nifedipine increased mean coronary sinus flow from 135 ml/min to 152 m/min, and reduced arterio-coronary sinus oxygen difference fr...