The aim of the study was to investigate the efficacy and safety of halometasone cream to treat chronic generalized eczema and the effects of halometasone cream on serum cortisol (COR) levels. Sixty consecutive outpatients diagnosed with chronic generalized eczema between January and April 2017 were included and divided into groups A, B, and C with a lesion area of 30%-40%, 41%-50%, and 51%-60%,...

Amiodarone AMD, a drug used in management of angina and refractory ventricular arrhythmia induces thyrotoxicosis in rat. The objective was to evaluate the role of Moringa Oleifera leaf methanolic exteract (MOE) administration and exposure to low doses of gamma-irradiation (LDR) as adjunctive strategy to modulate AMD associated thyrotoxicosis. The experiment started by rats i.p administration of...

Photosensitization properties of coronene-purine (Cor-P) hybrids for photodynamic therapy (PDT) have been investigated in this work. Eight hybrid Cor-P models have been designed by the additional of adenine (A) and guanine (G) nucleobase to Cor species. The evaluated absorption and emission energies indicated that the singular models are not good at all for PDT process whereas their hybrid mode...

This study compared the effects of postoperative pain and inflammation reaction after preventive laparoscopic-assisted gastropexy (LAG) and incisional gastropexy (IG) in 10 clinically normal Beagles. Surgical time, incision length, visual analog scale (VAS) score, University of Melbourne Pain Scale (UMPS) score, and plasma C-reactive protein (CRP), plasma cortisol (COR), and serum interleukin-6...

BACKGROUND We aimed to evaluate the effect of different capnoperitoneum pressures on stress responses in pediatric laparoscopic inguinal hernia repair. METHODS In this prospective randomized controlled study, 68 children with indirect inguinal hernia who underwent high ligation of hernia sac were randomly divided into 3 groups: high-pressure group (12 mm Hg, HP group, n = 26); low-pressure gr...

To investigate the effects of physical agents on the levels of stress hormones in patients with osteoarthritis (OA).Transcutaneous electrical nerve stimulation, hot packs, and therapeutic ultrasound were applied to the lumbar region and knees of patients with OA. Blood samples were taken for the measurement of the serum levels of glucose, insulin (INS), growth hormone (GH), prolactin (PRL), cor...

Introduction: ghrelin is a potent orexigenic agent in rodents and humans. Some studies have shown that ghrelin participates in the adaptive response to weight loss and plasma concentration of ghrelin rises with dieting. On the other hand, weight loss and fasting is accompanied by increased levels of epinephrine and cortisol. In this study, we investigated the effects of epinephrine and cortisol...

Abstract Introduction Racemic ketoconazole (RK) is a steroidogenesis inhibitor used for treatment of Cushing’s syndrome. Levoketoconazole (COR-003), the pure 2S,4R enantiomer, potentially more potent and safe compared to RK. We in vitro effects levoketoconazole RK on adrenocortical pituitary adenoma cells. Materials methods HAC15 cells 15 primary human neoplastic cultures (+/− ACTH), murine (At...

This study sought to characterize the effect of density stress on greater amberjack ( Seriola dumerili ) survival determine an optimal transport density. To achieve this, this experiment simulated conditions fish (body length: 4.09 ± 1.00 cm; weight: 0.9 0.05 g) using closed oxygen at 5 different densities (D1 = 1.125 kg/m 3 , D2 2.25 D3 3.375 D4 4.5 and D5 6.75 for 8 hours, after which biochem...

Lateolabrax maculatus is an important economic fish species in China. It a eurysaline and can survive grow water environment with varieties of salinity. practical significance to study the tolerance adaptability L. maculatus, because it usually suffers from sudden increase or decrease salinity aquaculture environment. This work investigated eff...