Klebsiella pneumoniae, Corynebacterium kutscheri, and Streptococcus pneumoniae are important pathogens that cause respiratory infections in laboratory rodents. In this study, we used species-specific triplex PCR analysis to directly detect three common bacterial pathogens associated with respiratory diseases. Specific targets were amplified with conventional PCR using the tyrB gene from K. pneu...

In mice, the presence or absence of a single complement (C') component, called hc(1), is controlled by two alleles at the Hc locus. The sera of mice which lack this C' component do not manifest C'-mediated immune hemolysis. When challenged with the common mouse pathogen, Corynebacterium kutscheri, mice possessing hemolytic C' fare slightly better than C'-deficient mice. When mice harboring late...

In this study, Corynebacterium kutscheri infection was reported in Sprague-Dawley rats that were stressed due to intense exercise during an experimental study. Weight loss, indifference the environment, fluffy feathers, and hunched posture observed affected rats. The lungs contained numerous, randomly distributed, variably sized, slightly raised, cream-colored caseopurulent foci. There occasion...