JOSEPH F. Ross, M.D., Editor

JOSEPH F. Ross, M.D., Editor

JOSEPH F. Ross, M.D., Editor

background: the aim of this study is to evaluate the association between different treatments and survival time of breast cancer patients using either standard cox model or stratified cox model. methods: the study was conducted on 15830 women diagnosed with breast cancer in british columbia, canada.  they were divided into eight groups according to patients’ ages and stage of disease either cox...

We describe a full maximum-likelihood fitting method of the popular single-factor Vasicek and Cox–Ingersoll–Ross models and carry this out for term-structure data from the UK and US. This method contrasts with the usual practice of performing a day-by-day fit. We also compare the results with some more crude econometric analyses on the same data sets. © 2000 Elsevier Science B.V. All rights res...

JOSEPH F. Ross, M.D., Editor

A group of regioisomeric 5-oxo-1,4,5,6,7,8 hexahydroquinoline derivatives possessing a COX-2 SO2Me pharmacophore at the para position of the C-2 or C-4 phenyl ring, in conjunction with a C-4 or C-2 phenyl (4-H) or substituted-phenyl ring (4-F,4-Cl,4-Br,4-OMe,4-Me, 4-NO2), were designed for evaluation as selective cyclooxygenase-2 (COX-2) inhibitors. These target 5-oxo-1,4,5,6,7,8 hexahydroquino...

Probabilistic properties of Cox processes of relevance for statistical modeling and inference are studied. Particularly, we study the most important classes of Cox processes, including log Gaussian Cox processes, shot noise Cox processes, and permanent Cox processes. We consider moment properties and point process operations such as thinning, displacements, and superpositioning. We also discuss...