Forensic artists use tissue thicknesses at well known landmarks on the craniofacial skeleton to generate a potential likeness of an individual from a skull. This is a very subjective and time consuming process. We present two prototype software packages: one for simulating the growth of a craniofacial skeleton either forwards or backwards in time, and the other for generating a facial reconstru...

The craniofacial skeleton is a complex and unique structure. The perturbation of its development can lead to craniofacial dysmorphology and associated morbidities. Our ability to prevent or mitigate craniofacial skeletal anomalies is at least partly dependent on our understanding of the unique physiological development of the craniofacial skeleton. Mouse models are critical tools for the study ...

AIM To develop a mathematical model that adequately represented the pattern of craniofacial growth in class III subject consistently, with the goal of using this information to make growth predictions that could be amenable to longitudinal verification and clinical use. MATERIALS AND METHODS A combination of computational techniques (i.e. Fuzzy clustering and Network analysis) was applied to ...

Growth of the craniofacial skeleton is a complex process controlled by both genetic and epigenetic factors, perturbations of which can lead to varying degrees of dysmorphology. Mouse models that recapitulate clinical craniofacial phenotypes are instrumental in studying the morphogenetic progression of diseases as well as uncovering their genetic and molecular bases. Commonly encountered phenoty...

the robert/sc (pseudothalidomide) syndrome is a rare autosomal recessive disorder, associated with phocomelia and craniofacial abnormalities. an anomalous fetus with lower limb phocomelia and micromelia, lumbar myeloschisis, upper limb and ribs defects and craniofacial abnormalities is reported whose diabetic mother took mebendazole and glibenclamide in early pregnancy. ultrasonographic finding...

The purpose of this study is to investigate the craniofacial morphology and the growth pattern in the frontal dimension of Japanese children with malocclusion. Nine hundred twenty-one subjects composed of 343 males and 578 females without any orthodontic treatment, age ranging from 7 years to 18 years, were classified into 3 types of facial skeletal pattern according to the A-B difference in la...

Recently, children born small for gestational age (SGA) with a catch-up growth failure, have been selected for high dose growth hormone (GH) treatment. In order to gain greater insight concerning dentofacial growth and maturation of these patients, and to evaluate the possible effects of high does GH administration on facial structures, craniofacial growth and dental maturation were evaluated i...