The purpose of this study was to investigate the effects of creatine monohydrate supplementation on exercise performance and contractile variables in aerobic-anaerobic training rats. Twenty 90-day-old male Sprague Dawley rats were divided into two groups - creatine (Cr) and controls (K). The creatine group received creatine monohydrate as a nutritional supplement, whereas the control group was ...

BACKGROUND Studies involving chronic creatine supplementation in elite soccer players are scarce. Therefore, the aim of this study was to examine the effects of creatine monohydrate supplementation on lower-limb muscle power in Brazilian elite soccer players (n = 14 males) during pre-season training. FINDINGS This was a randomized, double-blind, placebo-controlled parallel-group study. Brazil...

Background Early research with beta-alanine (b-ALA) supplementation has shown increases in muscle carnosine as well as improvements in body composition, exercise performance and blood lactate levels. Creatine monohydrate supplementation has been extensively researched for its effects on anaerobic exercise performance. Recently, studies have examined the combined effects b-ALA and creatine suppl...

The purpose of this study was to examine the effects of acute creatine-monohydrate supplementation on soccer-specific performance in young soccer players. Twenty young male soccer players (16.6 +/- 1.9 years) participated in the study and were matched and allocated to 2 randomly assigned trials: ingesting creatine-monohydrate supplement (3 x 10-g doses) or placebo for 7 days. Before and after t...

BACKGROUND Use of creatine has become widespread among sportsmen and women, although there are no conclusive evidences concerning possible health risks of long-term creatine supplementation. THE AIM OF THE STUDY To investigate long-term effects of creatine monohydrate supplementation on clinical parameters related to health. METHODS Eighteen professional basketball players of the first Span...

Abstract Background & Aims: In regard to the limited studies about the effect of creatine on exercise-induced inflammatory responses, the present study was conducted to identify the effect of creatine monohydrate loading on response of serum C-reactive protein (CRP), interleukin-6 (IL-6) and peripheral blood leucocytes following one bout downhill running in male mountain climbers. Methods: Twen...

Description Creatine is a naturally occurring amin (~1 g/day-1 [~0.04 oz.]) occurs in the glycine, arginine, and methionine. Cr daily requirement of ~2 to 3 g [~0.1 o Approximately 3 to 5 g [~0.1 to 0.2 o uncooked meat or fish. Dietary creat enters the bloodstream. Most (95 pe muscle. Sixty to seventy percent of s phosphocreatine (PCr), which is effe the anaerobic production of adenosin g [~4 o...

OBJECTIVES Creatine plays a pivotal role in brain energy homeostasis, and altered cerebral energy metabolism may be involved in the pathophysiology of depression. Oral creatine supplementation may modify brain high-energy phosphate metabolism in depressed subjects. METHODS Eight unipolar and two bipolar patients with treatment-resistant depression were treated for four weeks with 3-5 g/day of...

1. The present study was undertaken to test whether creatine given as a supplement to normal subjects was absorbed, and if continued resulted in an increase in the total creatine pool in muscle. An additional effect of exercise upon uptake into muscle was also investigated. 2. Low doses (1g of creatine monohydrate or less in water) produced only a modest rise in the plasma creatine concentratio...

This study investigated the effects of creatine and sodium bicarbonate coingestion on mechanical power during repeated sprints. Nine well-trained men (age = 21.6 ± 0.9 yr, stature = 1.82 ± 0.05 m, body mass = 80.1 ±12.8 kg) participated in a double-blind, placebo-controlled, counterbalanced, crossover study using six 10-s repeated Wingate tests. Participants ingested either a placebo (0.5 g·kg(...