INTRODUCTION The authors' center recently changed their pretransfusion testing protocol from "conventional" type and screen (TS) with anti-human globulin (AHG) crossmatch (Policy A) to TS with immediate-spin (IS) crossmatch (Policy B). Red blood cell (RBC) units were issued after compatible IS crossmatch as and when required instead of AHG crossmatch. This study was conducted to compare the eff...

OBJECTIVES Complement-dependent cytotoxic crossmatch is an important indicator for kidney transplant. However, there is controversy about treatment for flow cytometry crossmatch-positive cases. MATERIALS AND METHODS This was a retrospective study of 127 living-donor kidney transplant recipients from May 2007 to July 2011. We divided patients into 115 flow cytometry crossmatch T-cell and B-cel...

  Background: Reservation of blood leads to blood wastage if the blood is not transfused. Therefore, in some centers only blood type and screen are evaluated. In this study, the efficacy of a blood crossmatch-to-transfusion ratio was measured and then compared with the standard levels. Methods: This prospective study was conducted during one year in a university hospital. During this period, 39...

In the preparation of patients for renal transplantation tests of human leucocyte antigen (HLA) sensitisation are performed to detect "unacceptable" HLA antigens that, if present on donor cells, would be expected to result in a positive crossmatch. Individuals bearing such specificities may then be excluded from consideration as donors. Unexpected positive crossmatch results are sometimes obtai...

In order to select recipients without donor-specific anti-HLA antibodies, the complement-dependent cytotoxicity crossmatch (CDC-CM) was established as the standard procedure about 40 years ago. However, the interpretability of this functional assay strongly depends on the vitality of isolated donors' lymphocytes. Since the application of therapeutic antibodies for the immunosuppressive regimen ...

background: to evaluate the present status of blood utilization and develop practice guidelines in teaching hospitals in northern iran. methods: we retrospectively analyzed the amount of blood prepared and used preoperatively for 11 elective procedures, from march 2010 to march 2011 in teaching hospitals in northern iran. study variables included the crossmatch transfusion ratio, the transfusio...

BACKGROUND Assessment of blood compatibility, typically by tube agglutination (TUBE) and hemolysis crossmatch or, less commonly, by blood typing and alloantibody screening, often is performed before blood transfusion in horses. In contrast, gel column (GEL) and immunochromatographic strip (STRIP) techniques are preferred for compatibility testing in dogs and cats. OBJECTIVE To determine the a...

BACKGROUND Reservation of blood leads to blood wastage if the blood is not transfused. Therefore, in some centers only blood type and screen are evaluated. In this study, the efficacy of a blood crossmatch-to-transfusion ratio was measured and then compared with the standard levels. METHODS This prospective study was conducted during one year in a university hospital. During this period, 398 ...

W E HAVE previously reported that the liver is unusually resistant to hyperacute rejection and that a positive T lymphocyte cross match at 37 DC (positive T-warm crossmatch) is not a contraindication for liver homotransplantation. 13 Since the last report,2 we have accumulated 36 additional liver homografts transplanted in the presence of positive T-warm crossmatches. The one-year survival of t...

background: reservation of blood leads to blood wastage if the blood is not transfused. therefore, in some centers only blood type and screen are evaluated. in this study, the efficacy of a blood crossmatch-to-transfusion ratio was measured and then compared with the standard levels. methods: this prospective study was conducted during one year in a university hospital. during this period, 398 ...