نتایج جستجو برای: cst

تعداد نتایج: 2458  

Journal: :Cell cycle 2014
Feng Wang Jason Stewart Carolyn M Price

Mammalian CST (CTC1-STN1-TEN1) is a telomere-associated complex that functions in telomere duplex replication and fill-in synthesis of the telomeric C-strand following telomerase action. CST also facilitates genome-wide replication recovery after HU-induced fork stalling by increasing origin firing. CTC1 and STN1 were originally isolated as a DNA polymerase α stimulatory factor. Here we explore...

2017
Masaki Miyazawa Hajime Takatori Tetsuro Shimakami Kazunori Kawaguchi Kazuya Kitamura Kuniaki Arai Koichiro Matsuda Taku Sanada Takeshi Urabe Katsuhisa Inamura Takashi Kagaya Hideki Mizuno Uichiro Fuchizaki Taro Yamashita Yoshio Sakai Tatsuya Yamashita Eishiro Mizukoshi Masao Honda Shuichi Kaneko

BACKGROUND AND AIM Relapse and diabetes mellitus (DM) are major problems for the prognosis of autoimmune pancreatitis (AIP). We examined the prognosis of type 1 AIP after corticosteroid therapy (CST)-induced remission in terms of relapse and DM. METHODS The study enrolled 82 patients diagnosed with type 1 AIP who achieved remission with CST. We retrospectively evaluated the relapse rate in te...

Journal: :The Journal of neuroscience : the official journal of the Society for Neuroscience 2003
Paul Schweitzer Samuel G Madamba George R Siggins

Cortistatin (CST) is a sleep-modulating peptide found exclusively in the brain. Although CST is closely related to somatostatin (SST) and binds to SST receptors, CST has effects on sleep and neuronal activity in cortex and hippocampus that differ from SST. To uncover the cellular mechanisms affected by CST, we studied the electrophysiological postsynaptic effects of CST and assessed its interac...

Journal: :American journal of physiology. Regulatory, integrative and comparative physiology 2007
Baohan Pan Matthew R Zahner Ewa Kulikowicz Lawrence P Schramm

Sympathetic preganglionic neurons and interneurons are closely apposed (presumably synapsed upon) by corticospinal tract (CST) axons. Sprouting of the thoracic CST rostral to lumbar spinal cord injuries (SCI) substantially increases the incidence of these appositions. To test our hypothesis that these additional synapses would increase CST control of sympathetic activity after SCI, we measured ...

Journal: :American journal of respiratory and critical care medicine 1998
P Pelosi D Tubiolo D Mascheroni P Vicardi S Crotti F Valenza L Gattinoni

We studied 16 patients with acute lung injury receiving volume-controlled ventilation to assess the relationships between gas exchange and respiratory mechanics before, during, and after 2 h in the prone position. We measured the end-expiratory lung volume (EELV, helium dilution), the total respiratory system (Cst,rs), the lung (Cst,L) and the thoracoabdominal cage (Cst,w) compliances (end-insp...

2018
Lara Bieler Lukas Grassner Pia Zaunmair Christina Kreutzer Lukas Lampe Eugen Trinka Julia Marschallinger Ludwig Aigner Sebastien Couillard-Despres

Following spinal cord injury, severe deficits result from damages to ascending and descending tracts, such as the corticospinal tract (CST) which is highly relevant for the motor execution in humans. Unfortunately, no curative treatment is available and intensive efforts are deployed in animal models, such as the CST transection model, to identify interventions providing functional regeneration...

Journal: :Molecular and cellular endocrinology 2008
Luis de Lecea

Cortistatin (CST) is a neuropeptide from the somatostatin (SRIF)/urotensin (UII) family named after its predominantly cortical expression and ability to depress cortical activity, which was discovered a decade ago. In vitro assays show CST is able to bind all five cloned somatostatin receptors and shares many pharmacological and functional properties with SRIF. However, distinct from SRIF, CST ...

Journal: :Brain research. Molecular brain research 1999
M Calbet A Guadaño-Ferraz A D Spier M Maj J G Sutcliffe R Przewłocki L de Lecea

Cortistatin (CST) is a presumptive neuropeptide that shares 11 of its 14 amino acids with somatostatin (SST). CST and SST are expressed in partially overlapping but distinct populations of cortical interneurons. In the hippocampal formation, most CST-positive cells are also positive for SST. In contrast to SST, administration of CST into the rat brain ventricles reduces locomotor activity and s...

2017
Zhi-gang Min Chen Niu Qiu-li Zhang Ming Zhang Yu-cheng Qian

OBJECTIVE To identify the optimal factors in diffusion tensor imaging for predicting corticospinal tract (CST) injury caused by brain tumors. MATERIALS AND METHODS This prospective study included 33 patients with motor weakness and 64 patients with normal motor function. The movement of the CST, minimum distance between the CST and the tumor, and relative fractional anisotropy (rFA) of the CS...

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