Background Monoclonal antibodies (Mabs) have been recently used for the treatment of virtually every debilitating disease. Packed-bed bioreactors have been used for the cultivation and production of a wide range of cell lines and biologics including MAbs. The principle behind a Packed-bed bioreactor is that the cells are being immobilized within a suitable stationary matrix which is represented...

Natural zeolite was used as a bed medium for plantation of lettuce seedlings and its effects on growth and chemical composition of red tilapia and lettuce were investigated in a pisciponic system. The place of study was the Aquatic Resources Technology Laboratory, Faculty of Agriculture, at the University Putra Malaysia, in 2002. The mean individual weight and biomass of fish in the treatment w...

A biofiltration process was used for degradation of vinyl chloride as a hazardous material in the air stream. Three biotrickling filters in series-parallel allowing uniform feed and moisture distribution all over the bed were used. Granular activated carbon mixed with compost was employed as carrier bed. The biological culture consisted of mixture of activated sludge from PVC wastewater treatme...

Retroviral pseudotype vector, derived from the murine leukaemia virus carrying the HIV-1 envelop protein MLV (HIV-1) were produced using a integrated, continuous cultivation and harvest process. A 200ml fix bed reactor was used to cultivate the anchorage dependent packaging cell line on macro-porous carriers until the maximum glucose uptake was reached. After starting the cultivation in batch m...

Pluripotent stem cells are possibly the best candidates for regenerative medicine, and somatic cell nuclear transfer (SCNT) is one of the viable options to make patient-specific embryonic stem cells. Till date efficacy of SCNT embryos is very low and requires further improvement like ideal oocyte activation and in vitro culture system. The aim of the present study was to evaluate ideal oocyte a...

Hospital-wide active surveillance for methicillin-resistant Staphylococcus aureus (MRSA) targeted to adult patients with a history of MRSA carriage within the past 5 years was performed in Juntendo University Hospital (JUH) over a 2-year period. In the first year, MRSA screening culture was ordered by physicians in charge. In the second year, infection-control practitioners (ICPs) took samples ...

background sufficient evidence is lacking about patient safety culture in iran. it is only by focusing on the culture of safety within healthcare and treatment institutes that improvements may be made in patient care services. conclusions given that “staffing” was the lowest rated element in patient safety culture, improving this element could help to increase patient safety culture in hospital...