optimization of the exploitation operation is one of the most important issues facing the mining engineers. since several technical and economic parameters depend on the cut-off grade, optimization of this parameter is of particular importance. the aim of this optimization is to maximize the net present value (npv). since the objective function of this problem is non-linear, three methods can b...

One of the most difficult problems in mining operation is how to determine optimum cut-off grades of ores at different periods over the lifespan of the mine that will maximize the net present value (NPV) of the mine. Maximizing the NPV of a mining operation, subject to different constraints is a nonlinear programming problem. Cut-off grade optimization is used to arrive at an operating strategy...

Cut-off grade is one of the very important technical and economic parameters, which affects the economic and social efficiency in a mine enterprise. It is also the basis of the deposits technical economy evaluation, feasibility study, mining planning and design and the foundation of the decision-making in mining investment. Thereby, cut-off grade optimization is one of the core contents and the...

Lack of point-of-care tests for tuberculosis (TB) result in diagnostic delay, and increased mortality and healthcare-related costs. The urine Determine(TM) TB-LAM point-of-care strip-test was evaluated in 335 prospectively-recruited hospitalised patients with suspected TB-HIV co-infection (group 1) and from 88 HIV-infected hospitalised patients with non-TB diagnoses (group 2). Cut-off point-spe...

Optimization of the exploitation operation is one of the most important issues facing the mining engineers. Since several technical and economic parameters depend on the cut-off grade, optimization of this parameter is of particular importance. The aim of this optimization is to maximize the net present value (NPV). Since the objective function of this problem is non-linear, three methods can b...

PURPOSE To evaluate the mutual inter-relationship of mitotic indices, argyrophilic nuclear organizer regions (AgNOR) count, Ki-67 and B-cell lymphoma 2 protein (bcl-2) in papillary urothelial bladder cancer (pUBC), and their correlation with grade and stage. To establish the cut-off values of these markers to detect high grade and muscle invasive bladder cancer. MATERIALS AND METHODS Fifty-fo...

Background: Prostate cancer has been reported as a worldwide important kind of cancer and the second most common cause of cancer-related mortality among men. Prostate-specific antigen (PSA) serum level is one of the most important markers of prostate cancer diagnosis. While PSA level helps predict the risk of prostate cancer development, researchers still looking for ways to increase the accura...

OBJECTIVE To determine the trade-off between the sensitivity and the specificity for high grade cervical intraepithelial neoplasia at hybrid capture 2 cut-off values above the standard ≥ 1 relative light units/cut-off level (rlu/co). DESIGN Systematic review. DATA SOURCES PubMed. STUDY SELECTION Randomised controlled trials in primary cervical screening using hybrid capture 2 testing in t...

Cut-off grade is an important conditioning parameter that determines the quantity and quality of recoverable reserves development efficiency. Today, Russian mining companies operate with certified requirements. By setting permanent requirements, government seeks to prevent depletion reserves, reduced production during periods falling prices, decreased budget revenues, expressing interests all m...