Cutaneous malignant melanoma represents the major cause of mortality among skin cancers. Metastasis-associated protein CD24 is a small, heavily glycosylated cell surface protein that is overexpressed in various human malignancies. The present study was designed to determine the roles of CD24 in cutaneous malignant melanoma. The levels of CD24 mRNA and protein in cutaneous malignant melanoma tis...

Malignant melanoma is one of the most dangerous forms of cutaneous malignancies [1] . It is classified as cutaneous melanoma and non-cutaneous melanoma based on the location of the lesion. Ultraviolet (UV) radiation exposure is a predisposing factor for cutaneous melanoma, although in other forms such as mucous and anorectal malignant melanomas, ultraviolet radiation does not play a significant...

 SUMMARY X. Pis a rare autosomal recessive genodermatosis characteriseJ by photophohia, severe solar sensitivity, cutaneous pigmentary changes, xerosis and early Jevdopment of mucocutaneous and ocular cancer particularly in sun exposeJ skin. Tumors whichinclude solar keratosis, cutaneous horn, keratoachanthoma, squamous and basal cell carcinoma, malignant melanoma and angioma may developeJ in...

Background and Objective: The primary goal of this study is to develop a rigorous understanding ofthe correlation between COX-2 expression and malignant melanoma prognostic factors. Material and Methods: In this cross-sectional study, we analyzed 60 cases of cutaneous malignant melanoma. The related stained slides were reviewed by two pathologists. The re...

Malignant melanoma (MSA) is a cancer of pigmented cells called melanocytes. Cutaneous malignant melanoma may occur in the nail bed or on the foot pads. Melanomas that arise from the haired skin of the body, legs, or eyelids are usually benign but in rare cases can exhibit aggressive behavior similar to those of the nail bed, foot pads or mouth. Malignant melanoma can be a very aggressive cancer...

During the past several decades, there has been a substantial increase in the incidence of cutaneous melanoma among all caucasian populations. The number of deaths due to cutaneous malignant melanoma has also increased in most fair-skinned populations throughout the world in the past few decades. Trends in melanoma incidence worldwide are examined. The most recent data on the mortality from cut...

The malignant transformation of a cystic teratoma is a rare event, occurring in about 0.2% to 1.8%. Primary malignant melanoma arising from the ovary is extremely rare. A primary melanoma in an ovarian cystic teratoma originates most frequently at the dermoepidermal junction, similar to a cutaneous melanoma. Though there are no standard adjuvant regimens for the treatment of primary malignant m...

utaneous foot melanoma is rare; it accounts for approximately 1% of all cutaneous melanoma and can be challenging to manage [1]. There are four main variants of cutaneous malignant melanomas (CMMs), superficial spreading melanoma (SSM), lentigo malignant melanoma (LMM), nodular melanoma (NM) and acral lentiginous melanoma (ALM). Superficial spreading melanoma accounts for approximately 65% of a...