نتایج جستجو برای: cyclooxygenase inhibition

تعداد نتایج: 338637  

Journal: :Current Pharmaceutical Design 2008

Journal: :Hypertension 2010
Carmen Capone Giuseppe Faraco Josef Anrather Ping Zhou Costantino Iadecola

Prostaglandin E(2) (PGE(2)) EP1 receptors (EP1Rs) may contribute to hypertension and related end-organ damage. Because of the key role of angiotensin II (Ang II) in hypertension, we investigated the role of EP1R in the cerebrovascular alterations induced by Ang II. Mice were equipped with a cranial window, and cerebral blood flow was monitored by laser-Doppler flowmetry. The attenuation in cere...

Journal: :Circulation 2015
Blerina Ahmetaj-Shala Nicholas S Kirkby Rebecca Knowles Malak Al'Yamani Sarah Mazi Zhen Wang Arthur T Tucker Louise Mackenzie Paul C J Armstrong Rolf M Nüsing James A P Tomlinson Timothy D Warner James Leiper Jane A Mitchell

BACKGROUND Cardiovascular side effects associated with cyclooxygenase-2 inhibitor drugs dominate clinical concern. Cyclooxygenase-2 is expressed in the renal medulla where inhibition causes fluid retention and increased blood pressure. However, the mechanisms linking cyclooxygenase-2 inhibition and cardiovascular events are unknown and no biomarkers have been identified. METHODS AND RESULTS T...

Journal: :مجله علوم اعصاب شفای خاتم 0
amirhooshang ansari department of university research, dental faculty, mashhad university of medical sciences, mashhad, iran maede shokri department of university research, dental faculty, mashhad university of medical sciences, mashhad, iran shamime asadi department of university research, dental faculty, mashhad university of medical sciences, mashhad, iran negin nejadali department of university research, dental faculty, mashhad university of medical sciences, mashhad, iran

tooth pulpal nerves include sympathetic and sensory nerves that originate from trigeminal ganglion .from the terminal of these sensory nerves neuropeptides are secreted that are neuromodulators and neurotransmitters. one of them is cgrp (calcitonin gene-related protein) which has a vasodilatory effect on pulpal vessels. near abscess and moderate injuries, this neuropeptide can lead to neural fi...

Journal: :basic and clinical neuroscience 0
shahedeh farahbakhsh sedigheh arbabian fatemeh emami banafsheh rastegar moghadam hassan ghoshooni ali noroozzadeh

introduction: it has been shown that the extract of elaeagnus angustifolia can inhibit inflammation and pain induced by formalin in mice and rats. the aim of the present study is to reach evaluations of possible cellular and molecular mechanisms of elaeagnus angustifolia extract in reducing pain and inflammation through examining the extract ability for inhibition of cyclooxygenase (cox) type 1...

Amirhooshang Ansari, Maede Shokri, Negin Nejadali, Shamime Asadi,

Tooth pulpal nerves include sympathetic and sensory nerves that originate from trigeminal ganglion .From the terminal of these sensory nerves neuropeptides are secreted that are neuromodulators and neurotransmitters. One of them is CGRP (Calcitonin gene-related protein) which has a vasodilatory effect on pulpal vessels. Near abscess and moderate injuries, this neuropeptide can lead to neural fi...

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