background: benzene is one of the important occupational pollutants. there are some reports about the leukemogenic effects related to low-level exposure to benzene. objective: to study the frequency of micronucleus (mn), nucleoplasmic bridge (nb), and nuclear budding (nbud) in the peripheral blood lymphocytes of petrochemical workers with low level exposure to benzene. methods: we enrolled 50 w...

objective: to evaluate the effect of cytoplasm transfer from mature oocytes to germinal vesicle(gv)s on promoting the maturation of cytoplasm of gv at the mrna level. materials and methods: sixty six in vitro fertilization (ivf) operations between june 2012 and november 2013 were included in this study. totally 120 gvs were obtained. normal gvs were categorized into 3 groups (n = 40) randomly: ...

tissue plasminogen activator (tpa) is a serine protease, which is composed of five distinct structural domains with 17 disulfide bonds, representing a model of high-disulfide proteins in human body. one of the most important limitations for high yield heterologous protein production in escherichia coli (e. coli) is the expression of complex proteins with multiple disulfide bridges. in this stud...