Triple-negative breast cancer (TNBC) is more aggressive and has poorer prognosis compared to other subtypes of cancer. Epithelial-to-mesenchymal transition (EMT) a process in which epithelial cells transform into mesenchymal-like capable migration, invasion, metastasis. Recently, we have demonstrated that lovastatin, 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitor lipid-lowering drug,...

Neurons rely on a unique organization of their cytoskeleton to build, maintain and transform extraordinarily intricate shapes. After decades research the neuronal cytoskeleton, it is exciting that novel assemblies are still discovered thanks progress in cellular imaging methods. Indeed, super-resolution microscopy has revealed axons lined with periodic scaffold actin rings, spaced every 190 nm ...

Cell-to-cell communication is crucial in coordinating diverse biological processes multicellular organisms. In plants, between adjacent cells occurs via nanotubular passages called plasmodesmata (PD). The PD passage composed of an appressed endoplasmic reticulum (ER) internally, and plasma membrane (PM) externally, that traverses the cell wall, associates with actin-cytoskeleton. coordination E...