BACKGROUND Uremic pruritus is a common, but unpleasant, complication of end-stage renal disease. The uremic burden may differ between hemodialysis (HD) and peritoneal dialysis (PD) patients. This difference may also change the clinical characteristics of uremic pruritus between the 2 modalities. In this study, we investigated the uremic pruritus between patients on HD and PD. METHODS A total ...

Itch (pruritus) is an unpleasant sensation that leads to the desire to scratch (1). Pruritus may compromise quality of life and sleep in affected individuals. Pruritus is similar to pain, in being a subjective symptom; assessment of its intensity is a key issue in evaluating severity and therapeutic outcome of patients with pruritic disorders of diverse origins (cutaneous, systemic, neuropathic...

BACKGROUND Pruritus is the most common side effect of epidural morphine analgesia. Diphenhydramine is a widely used agent for the treatment of urticarial pruritus. Nalbuphine is a mixed opioid agonist-antagonist and has been reported to be effective in treating opioid-induced pruritus. We compared the effectiveness of intramuscular diphenhydramine and nalbuphine for the prevention of epidural m...

Introduction: Although uremic pruritus is not a life-threatening problem itself, it affects the quality of life and daily activities patients negatively changes patient's adaption to disease. 
 Methods: This descriptive analytical study was conducted with 219 who underwent hemodialysis in State Hospital, University Hospital units private dialysis center met criteria. Research data were col...

Introduction A validated assessment of pruritus intensity is an important but still difficult clinical problem due to a subjective nature of this sensation. Objective The aim of this study was the creation and validation of new itch severity questionnaire assessing pruritus intensity. Material and Methods A total of 148 patients with pruritic dermatoses were asked to assess pruritus intensi...

Uremic pruritus is still a common phenomenon in patients with end-stage renal failure, however, there is no effective treatment of choice for this condition. This study was undertaken to evaluate the efficacy and tolerance of the cream with structured physiological lipids (DMS, Derma Membrane Structure) and endogenous cannabinoids in controlling pruritus in patients on maintenance hemodialysis....

Chronic pruritus is a complex multifactorial symptom associated with many different diseases that represents a diagnostic and therapeutic challenge for physicians. In order to better manage chronic pruritus, a detailed medical history, individualized diagnostic procedures and treatment approaches are necessary. Treatment should not only take itch into consideration, but also scratching-induced ...

Finkelstein W, Isselbacher KJ. Cimetidine. N EnglJ_ Med 1978;299:992-6. 2 Harrison AR, Littenberg G, Goldstein L, Kaplowitz N. Pruritus, cimetidine and polycythemia. N EnglJ Med 1979;300:433-4. 3 Zappacosta AR, Hauss D. Cimetidine doesn't help pruritus of uremia. N EnglJ Med 1979;300:1280. 4 Easton P, Galbraith PR. Cimetidine treatment of pruritus in polycythemia vera N EnglJ Med 1978;299:1134....

INTRODUCTION Paraneoplastic pruritus is defined as pruritus that occurs before or during the natural evolution of a hematologic disease. The reported prevalence is 30% in patients with Hodgkin's lymphoma. The severity of this pruritus has a very negative impact on patients' quality of life. Very few studies have been made to examine the efficacy of pharmacological treatments for this type of pr...

INTRODUCTION Uremic pruritus is one of the most common disabling symptoms in patients with end-stage renal disease. We aimed to study the effect of montelukast sodium for the treatment of uremic pruritus lasting more than 3 months in patients undergoing hemodialysis and compare it with placebo. METHODS AND MATERIALS Eighty patients undergoing hemodialysis at 3 centers in Shiraz, Iran, were re...