Glucocorticoids affect glucose metabolism in adults and fetuses, although their effects on materno-fetal glucose partitioning remain unknown. The present study measured maternal hepatic glucose handling and placental glucose transport together with insulin signalling in these tissues in mice drinking corticosterone either from day (D) 11 to D16 or D14 to D19 of pregnancy (term = D21). On the fi...

Liquid chromatography coupled to atmospheric pressure chemical ionization (APCI) and electrospray ionization (ESI) mass spectrometry (MS), in parallel, was used for simultaneous detection of bovine milk sphingolipids (BMS). APCI-MS mass spectra exhibited mostly ceramide-like fragment ions, [Cer-H(2)O+H](+) and [Cer-2H(2)O+H](+), which were used to identify individual molecular species of BMS ac...

Shear connectors are used in steel beam-concrete slabs of composite frame and bridge structures to transfer shear force according to design loads. The existing Y-type perfobond rib shear connectors are designed for girder slabs of composite bridges. Therefore, the rib and transverse rebars of the conventional Y-type perfobond rib shear connectors are extremely large for the composite frames of ...

In silico ADME Toxicity profiling showed an interesting results against the resveratrol and its designed ligands (D1-D16), that these ligands were permeable by intestinal (Human Colonic Carcioma Cell Line) CaCo2 cell line and D8, D9, D11, D13, D14, D15, D16 were inhibitor of CYP2C19 microsomal enzyme which were may be active against breast cancer cell line, as the D13, D16 were belong to the pg...

LC3 - the mammalian homolog of Atg8 - was found as autophagosome membrane binding protein in mammals and widely used as an autophagosomal marker. LC3A, B and C show different expression patterns in each tissue. The aim of this study was to reveal the differences of expression patterns among LC3 families in mouse placenta under normal condition and nutrient starving condition. LC3A and B were hi...

Recent pharmacological studies have shown the importance of trace amine-associated receptor, type 1 (TAAR1), a subtype of trace amine receptors, to be a prospective target receptor for novel neuroleptics. Socalled D-neuron (trace amine (TA) neuron) is the ligand neuron of TAAR1. In 1984, Jaeger et al. specified D-neuron groups from D1 (the spinal cord) to D14 (the bed nucleus of stria terminali...

Abstract. In this paper the effect of asymmetric rolling on possibility increasing technological plasticity aluminum alloys was investigated. The experimental research carried out a laboratory mill with an individual drive work rolls creating speed ratio from 1.0 to 5.0. It shown that increase 5.0 significantly reduce force in comparison symmetric rolling. Rolling decreased 1.9 times for alloy ...

Recent reports have indicated human embryonic stem cells-derived midbrain dopamine (mDA) neurons as proper cell resources for use in Parkinson's disease (PD) therapy. Nevertheless, no detailed and systematic study has been conducted to identify which differentiation stages of mDA cells are most suitable for transplantation in PD therapy. Here, we transplanted three types of mDA cells, DA progen...

No. D16.J.M. Snyder, J. Food Lipids, 2 ( 1995) 25.J.W. King. J.H. Johnson and F.J. Eller, Anal. Chem., 67 ( 1995) 14.J.W. King, J.H. Johnson, S.L. Taylor, W.L. Ortonand M.L. Hopper, J. Supercrit. Fluids, 8 (1995)