A link between dermatomyositis and neoplasia has long been suspected. The precise incidence of this association remains controversial, owing to varying criteria used to diagnose dermatomyositis. Although juvenile dermatomyositis is believed to display no association with neoplasm, there have been few reported cases of dermatomyositis associated with tumors of any kind in pediatric age group (1-...

UNLABELLED Aim of this study was to identify the association between dermatomyositis and malignancy in China. METHODS We retrospectively analyzed the clinical data of 115 cases of dermatomyositis associated with malignancy. RESULTS From 1974 to 2008, there were 678 cases of dermatomyositis collected from the Second Affiliated Hospital, Sun Yat-Sen University, China. Among them, 115 cases (1...

OBJECTIVES: To analyse the frequency of metabolic syndrome in young adult female dermatomyositis patients and its possible association with clinical and laboratory dermatomyositis-related features and serum adipocytokines. METHOD: This cross-sectional study included 35 dermatomyositis patients and 48 healthy controls. Metabolic syndrome was defined according to the 2009 Joint Interim Statemen...

Dermatomyositis is a chronic inflammatory myopathy with severe prognosis. A 57-year-old woman suffering from dermatomyositis is presented who, in the course of the disease, developed acute spontaneous esophageal rupture due to dermatomyositis involvement of the esophagus. She was successfully treated with total esophagectomy and stomach interposition. This is the first report of spontaneous rup...

Expression of microRNA (miRNA) in the skin in dermatomyositis has not previously been studied in detail. In this study, we performed miRNA array analysis using miRNAs purified from dermatomyositis-involved skin and normal skin, and found that several miRNAs were up- or down-regulated in dermatomyositis skin. Among them, we focused on miR-7, one of the most down-regulated miRNAs in dermatomyosit...

OBJECTIVE It is uncommon for dermatomyositis to be associated with papillary thyroid cancer. We report an unusual case of papillary thyroid cancer presenting with dermatomyositis. METHODS The case history, imaging and laboratory data is reviewed. RESULTS We report the case of a 62-year-old female with a prior history of dermatomyositis and breast cancer who presented with a recurrent episod...

BACKGROUND The association between dermatomyositis and breast carcinoma has not been fully evaluated yet. The aim of the study was to clarify characteristics of the association between these two diseases. METHODS The medical records of 128 patients with dermatomyositis or polymyositis from 1990 to 1998 were retrospectively reviewed. Eight patients (6.3%) were identified with dermatomyositis w...

Dermatomyositis is well known to be associated with several types of malignancy and patients with dermatomyositis have higher rates of mortality from cancer. Although rare in Japan, head and neck cancer, especially nasopharyngeal cancer, is the predominant type of cancer associated with dermatomyositis in several areas in Asia, including Hong Kong and Singapore. Here we report two cases of head...

•Dermatomyositis in ovarian cancer responds to treatment with neo-adjuvant carboplatin and paclitaxel in conjunction with corticosteroids.•Recurrence of dermatomyositis symptoms is often the first sign of relapsed disease.•Prognosis of ovarian cancer in context of dermatomyositis is poor.

Dermatomyositis is associated with various types of malignancy. However, the association of dermatomyositis with lung neuroendocrine carcinoma is rare. We herein report a case of dermatomyositis with lung neuroendocrine carcinoma.