Substance abuse is an important health, psychological and social problem in the world. Gabapentin is a new antiepileptic drug. It is used in neurological and psychiatric disorders. Moreover the effects of gabapentin on increasing the analgesic effect of morphine and its inhibitory effects on dopamine release due to morphine in animal models have been proved. In the present study, the effect of ...

substance abuse is an important health, psychological and social problem in the world. gabapentin is a new antiepileptic drug. it is used in neurological and psychiatric disorders. moreover the effects of gabapentin on increasing the analgesic effect of morphine and its inhibitory effects on dopamine release due to morphine in animal models have been proved. in the present study, the effect of ...

STUDY OBJECTIVE We evaluate the effectiveness and safety of emergency medical services (EMS) provider use of a checklist to triage alcohol-inebriated patients directly to a detoxification facility, rather than an emergency department (ED). METHODS A retrospective cohort study was conducted of all patients evaluated during a 2-year period, from 2003 to 2005, by EMS providers who used a detoxif...

Opioid dependence is a major health problem and a cause of increasing concern to physicians and other health professionals worldwide. A crucial first step in intervention is detoxification. Recent trends in medical practice have seen the emergence of newer techniques that claim to accelerate the detoxification procedure and ensure prevention of relapse by rapid induction onto maintenance treatm...

BACKGROUND/AIM The need for sensitive biological markers to detect and prove recent drinking has been the focus of many research groups. The aim of our study was to investigate the alterations of biological markers in a population of alcohol dependent individuals during the detoxification period. PATIENTS AND METHODS Fifty-two alcohol-dependent individuals were admitted for alcohol detoxifica...

The paper examines trends in the use of inpatient substance abuse detoxification provided at general hospitals using data from the Healthcare Utilization and Cost Project - National Inpatient Survey. Most persons who received inpatient detoxification did not also receive rehabilitation while an inpatient. The percentage receiving rehabilitation declined between 1992 and 1997 from 38.9% to 21.1%...

Opioid dependence is a major health problem and a cause of increasing concern to physicians and other health professionals worldwide. A crucial first step in intervention is detoxification. Recent trends in medical practice have seen the emergence of newer techniques that claim to accelerate the detoxification procedure and ensure prevention of relapse by rapid induction onto maintenance treatm...

BACKGROUND GABAergic anticonvulsants have been recommended for the treatment of alcohol dependence and the prevention of relapse. Several studies have demonstrated topiramate's efficacy in improving drinking behaviour and maintaining abstinence. The objective of the present open-label controlled study was to assess efficacy and tolerability of low-dose topiramate as adjunctive treatment in alco...

This paper describes the use of morphine to reduce severity and duration of withdrawal symptoms while undergoing rapid opiate detoxification (ROD) from methadone under medical supervision. A pilot study of 24 randomly selected patients, some using heroin and others being dosed on methadone were surveyed between two months and three months from the time of their detoxification to gauge subjectiv...

“Il Principe” (the Prince) is the nickname given to a spectacular Mid Upper Palaeolithic (Gravettian) burial discovered at Arene Candide, Italy in 1942. Arene Candide is a large cave located about 90 m above sea level on the slope of the Caprazoppa promontory, along the Ligurian coast near Finale Ligure (Savona, Italy). The cave is named after a dune of white siliceous sand of aeolian origin, b...