Nanobiosensors can be built via functionalization of atomic force microscopy (AFM) tips with biomolecules capable of interacting with the analyte on a substrate, and the detection being performed by measuring the force between the immobilized biomolecule and the analyte. The optimization of such sensors may require multiple experiments to determine suitable experimental conditions for the immob...

BACKGROUND When applied at the correct plant stage and dose, herbicides are highly toxic to plants. At reduced, low herbicide doses (below the recommended dose) plants can survive and display continuous and quantitative variation in dose-survival responses. Recurrent (directional) selection studies can reveal whether such a phenotypic variation in plant survival response to low herbicide dose i...

A random survey of 264 cropping fields in the Western Australian wheat belt was conducted to determine the extent of rigid ryegrass resistance to commonly used acetolactate synthaseand acetyl-CoA carboxylase-inhibiting herbicides. Rigid ryegrass infestation density was assessed and seed samples collected and subsequently tested for resistance to diclofop-methyl, clethodim, chlorsulfuron, and su...

Herbicidal activity of aryloxyphenoxypropionate and cyclohexanedione herbicides (graminicides) has been proposed to involve two mechanisms: inhibition of acetyl-coenzyme A carboxylase (ACCase) and depolarization of cell membrane potential. We examined the effect of aryloxyphenoxypropionates (diclofop and haloxyfop) and cyclohexanediones (sethoxydim and clethodim) on root cortical cell membrane ...

INTRODUCTION We assessed the relationship between hypospadias and proximity to agricultural pesticide applications using a GIS-based exposure method. METHODS We obtained information for 354 cases of hypospadias born between 1998 and 2002 in eastern Arkansas; 727 controls were selected from birth certificates. We classified exposure on pounds of pesticides (estimated by crop type) applied or p...

Tandem mass spectrometry (MS) was used to detect herbicide residues in wild populations of amphipods collected from microcosms spiked with a single pulse of either Avadext-BW (triallate) or HoeGrasst (diclofop-methyl) at three different concentrations (1.0, 10.0, and 100.0 mg·L21). Independent confirmations of both herbicides were obtained by spiking amphipod tissues with 50 pg of authentic sta...

A general model of crop yield response to herbicide application is proposed. The model includes three components: the effect of herbicide dosage on weed density, the effect of surviving weed density on crop yield and the effect of herbicide directly on the crop. The model is used to estimate the response of wheat yield to application of diclofop-methyl to control ryegrass .(Lolium rigidum) in A...

Acetyl-CoA carboxylases (ACCs) are crucial for the metabolism of fatty acids, making these enzymes important targets for the development of therapeutics against obesity, diabetes, and other diseases. The carboxyltransferase (CT) domain of ACC is the site of action of commercial herbicides, such as haloxyfop, diclofop, and sethoxydim. We have determined the crystal structures at up to 2.5-A reso...