نتایج جستجو برای: dig
تعداد نتایج: 2004 فیلتر نتایج به سال:
Bispecific antibodies that bind cell-surface targets as well as digoxigenin (Dig) were generated for targeted payload delivery. Targeting moieties are IgGs that bind the tumor antigens Her2, IGF1R, CD22, or LeY. A Dig-binding single-chain Fv was attached in disulfide-stabilized form to C termini of CH3 domains of targeting antibodies. Bispecific molecules were expressed in mammalian cells and p...
OBJECTIVE To study the effects of berberine (BBR) on the pharmacokinetics of digoxin (DIG) in rats. METHOD Rats were randomly assigned into DIG, low dose-BBR, middle dose-BBR and high dose-BBR group. After singe or a 2-week ig pretreatment with BBR, serum DIG concentration was determined by radioimmunoassay. Pharmacokinetic calculations were performed on each individual set of data using 3P97...
Every day we receive lots of information through our senses that is lost forever, because it lacked the strength or the repetition needed to generate a lasting memory. Combining the emerging Internet of Things and lifelogging sensors, we believe it is possible to build up a Digital Memory (Dig-Mem) in order to complement the fallible memory of people. This work shows how to realize the Dig-Mem ...
The DIG interface defines a protocol for the communication of Description Logic (DL) applications. The current DIG 1.1 specification has some shortcomings, which gave rise to the definition of its successor DIG 2.0. In this paper, we introduce the DIG 2.0 Reference Middleware. It allows for the integration of applications that comply with any of the two language versions. In addition to a langu...
Strong antigenic changes were induced in two LI 210 leukemia lines (L1210 Cr and L1210 Ha) after several passages in CDF, and BDF, mice treated with 5-(3,3-dimethyl-l-triazeno)imidazole-4-carboxamide (DIG). The leukemic cells of both lines originally compatible with DBA/2 and related hybrid hosts elicited a pronounced allograft reaction in the same animals. The LI 210 Cr line was sensitive to t...
It seems kind of strange that eating parasitic worms causes a cure rather than a disease. Yet, this fact is no stranger than many other man-bites-dog stories about "real life" in contemporary times. Such stories arise at moments of changing equilibria in the processes of the social construction of reality. They are especially evident during periods of intense dialectic in which long held theses...
Experiments were conducted to evaluate digestible (dig) Lys requirements of male and female broiler chickens from 49 to 63 d of age. A dose-response diet consisting of corn, soybean meal, and corn gluten meal was formulated to be adequate in dig amino acid concentrations with the exception of Lys. L-Lysine . HCl was added to the dose-response diet to create 7 experimental diets. Concentrations ...
Background. Daclatasvir (DCV) is a potent hepatitis C virus (HCV) NS5A replication complex inhibitor with pangenotypic (GT 1-6) activity in vitro. Asunaprevir (ASV) is a selective NS3 protease inhibitor with in vitro activity against GT 1, 4, 5 and 6. These two direct-acting antivirals (DAA) are in phase 3 development and regulatory review as a dual-DAA regimen (DCV + ASV) for the treatment of ...
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