BACKGROUND Convection enhanced delivery (CED) is an emerging form of direct brain infusion therapy employed in human functional and restorative neurosurgery clinical trials delivering protein, viral vectors for gene therapy, and siRNA. PURPOSE Pressure monitoring has become a vital tool in ensuring infusion safety and success. We report details of this benchmark first trial of the use of a le...

The octopus circulatory system is atypical of the molluscs, with a medially situated ventricle generating high arterial blood pressures (Johansen & Martin, 1962; Wells, 1979). Using free-moving Octopus dofleini, Johansen & Martin (1962) demonstrated the presence of an accessory branchial pump, boosting the venous blood pressure, between the anterior vena cava and the afferent branchial vessel. ...

Intravenous pressure bag Theatre table TECHNiQUE An intravenous fluid pressure bag is placed under the pelvis at the start of the procedure. To protect the patient from direct contact with the bag and the plastic components of the device, the bag is placed under a gel pad. The pump protrudes over a lateral edge of the operating table. Having reached the point when the modified position is requi...

OBJECTIVE Various types of rotary blood pumps (axial flow, centrifugal) have been introduced into clinical use recently. These pumps have different pressure-flow characteristics, and some investigators have noted that a limited pump flow rate and less pulsatility are the problems with the axial flow devices. METHODS A new implantable centrifugal blood pump was developed that has an extremely ...

A water distribution network is subjected to various abnormal conditions such as pipe breaks, pump failures, excessive demands etc. in the design period. Under such conditions, the network may not be able to meet required demands at desired pressures, and becomes deficient. Traditional network analysis assumes nodal demands to be satisfied and available nodal pressures are calculated. However, ...

In the working process of axial piston pump, composite multi-degree freedom motion slipper and its coupling, as well complex conditions, cause to overturn collide irregularly with coupling. The overturning leads partial abrasion slipper, magnitude force generated by direct solid contact between swash plate significantly impacts wear speed slipper. This article is based on rigid-flexible couplin...

This research adopts the quasi three-dimensional hydraulic design method for the impeller of high specific speed mixed-flow pump to achieve the purpose of verifying the hydraulic design method and improving hydraulic performance. Based on the two families of stream surface theory, the direct problem is completed when the meridional flow field of impeller is obtained by employing iterative calcu...

While the issue on Direct Containment Heating (DCH) was resolved for US reactor plants in the 1990s it was found that the consequences of DCH processes are strongly dependent on the reactor cavity configuration. Therefore, an experimental and analytical program was started in 1998 to investigate melt ejection scenarios for typical German and European reactor designs. Six experiments have been p...

Sarcomeric contraction in cardiomyocytes serves as the basis for the heart's pump functions in mammals. Although it plays a critical role in the circulatory system, myocardial sarcomere length (SL) change has not been directly measured in vivo under physiological conditions because of technical difficulties. In this study, we developed a high speed (100-frames per second), high resolution (20-n...