background: we conducted a retrospective analysis to evaluate the impact of omission of supraclavicular radiotherapy on supraclavicular failure rate and treatment outcomes in n1 breast cancer patients with evaluation of prognostic factors that affected supraclavicular recurrence free survival. methods: this study analyzed the medical records of 109 patients with n1 breast cancer. all patients u...

cutaneous hodgkin’s lymphoma is a rare disease (0.5% to 3.4%) which tends to be in the setting of an advanced disease and has a poor prognosis. treatment of patients with cutaneous involvement of hodgkin’s lymphoma is according to dissemination of disease (systemic or localized therapy). the majority of data in this context are based on individual case reports or literature reviews. we have rep...

the purpose of this study was to describe the feasibility of a combined preoperative chemoradiation program ib-iia, bulky and suspicious iib by radical surgery in patients with stage ib-iib cervical cancer. from september 1999 to april 2002, 30 patients with carcinoma of the cervix were treated with preoperative external beam radiotherapy of 45 gy in 5 weeks. patients received concurrent contin...

background : we conducted a retrospective analysis to investigate the clinical outcome of combined modality therapy using multiagent chemotherapy, nephrectomy, and radiotherapy in treatment of children with wilms' tumor. methods : this study was conducted on 91 cases of newly diagnosed wilms' tumor from january 2001 until february 2012. patients were categorized into two groups according to tre...

background: osteosarcoma is the most common bone sarcoma, and the third most common malignancy in children and adolescents. before 1970, amputation was the sole treatment. eighty percent of patients died from metastatic diseases, most commonly in the lungs. over the past three decades, effective neoadjuvant (preoperative) and adjuvant (postoperative) chemotherapy protocols have improved the abi...

hematopoietic cell transplantation (hct) is an accepted treatment for acute myeloid leukemia (aml) in first remission, the treatment of choice for chronic myeloid leukemia (cml) and high risk groups of all who relapse with conventional chemotherapy. we assessed results of hct for pediatric leukemia in our center. a total of 92 children, 63 with diagnose of aml, 23 with all and 6 with cml receiv...

this study focused on triple-negative breast cancer (tnbc) that is characterized by the lack of expression of estrogen receptor (er), progesterone receptor (pr), and human epidermal growth factor receptor 2 (her-2). the primary goal of this study was to describe the relation between triple-negative receptor status and survival. this is the first study about triple-negative breast cancer in our ...

background: although multifocal and multicentric breast cancers are a common entity, their clinical behavior is not well characterized. with the widespread use of mammographic screening and improved sensitivity of imaging modalities, the detection of multifocal and multicentric breast cancers is likely to continuously increase. many studies have consistently shown a correlation between multifoc...