Preeclampsia is associated with increased peripheral resistance. This study was performed to determine whether an increase of venous distensibility occurs as well in preeclampsia. We obtained venous distensibility by measuring the venous pressure-volume relation in the forearm with a water-filled plethysmograph. Twenty-one women with normal pregnancy, 12 women with severe preeclampsia, and 8 wo...

Purpose Large trans-lamina cribrosa pressure differences (TLCPD) have been suggested to play a role in the development of normal-tension glaucoma. To avoid substantial increases TLCPD upright postures, we hypothesize that collapse optic nerve subarachnoid space (ONSAS) protects eyes from large TLCPDs when stand up, i.e., by preventing low cerebrospinal fluid pressures around nerve. In this stud...

There are abnormalities in renous structure and function in animal models of hypertension. In humans with borderline hypertension, there is a redistribution of blood from the periphery to the central circulation that may be produced in part by a decrease in peripheral Tenons distensibility. In this study we used a water-filled pletbysmograph to determine forearm renous distensibility in nine yo...

This study aimed to quantify arterial volume distensibility in patients with branch retinal vein occlusion (BRVO) in comparison with normal subjects and to investigate factors associated with their differences. 40 normal subjects and 30 BRVO patients were studied. Brachial-ankle pulse wave velocity (baPWV) was measured to determine arterial volume distensibility. In comparison with the normal s...

BACKGROUND Atherosclerosis develops from childhood, but the determinants of this preclinical stage remain uncertain. We examined the relations of classic coronary risk factors, adiposity and its associated metabolic disturbances, to arterial distensibility (a marker of early arterial disease) in 13- to 15-year-olds, some of whom had previously been studied at ages 9 to 11 years. METHODS AND R...

The aims of this study were to compare perineal distensibility between women with twin and singleton pregnancies and to correlate these women's perineal distensibility with anthropometric data. This prospective cross-sectional case-control study was conducted among nulliparous women, of whom 20 were pregnant with twins and 23 with a single fetus. Perineal distensibility was evaluated in the thi...

Resting heart rate is an easily measured, noninvasive vital sign that is associated with cardiovascular disease events. The pathophysiology of this association is not known. We investigated the relationship between resting heart rate and stiffness of the carotid (a peripheral artery) and the aorta (a central artery) in an asymptomatic multi-ethnic population. Resting heart rate was recorded at ...

Background Arterial distensibility can be measured non-invasively by cardiovascular magnetic resonance (CMR) in various arterial territories. However, no information is available comparing distensibility in different anatomical territories in individual patients. Therefore, we sought to compare CMR measurements of the distensibility of the coronary and carotid artery, and ascending aorta (AA) i...

Compliance and distensibility are wall properties of large arteries, which may play a role in cardiovascular disease. The purpose of this study was to investigate whether the influence of age on these vessel wall properties differs between vascular territories and is gender-dependent. In a population sample of 498 men and women 20 to 79 years of age, diameter, distensibility, and compliance coe...

Airway distensibility appears to be unaffected by airway smooth muscle (ASM) tone, despite the influence of ASM tone on the airway diameter-pressure relationship. This discrepancy may be because the greatest effect of ASM tone on airway diameter-pressure behavior occurs at low transpulmonary pressures, i.e., low lung volumes, which has not been investigated. Our study aimed to determine the con...