Distraction osteogenesis (DO) is one of the most dramatic in vivo applications of mechanical stimulation as a means of inducing bone regeneration. A simple and reproducible murine model of tibia distraction osteogenesis was developed using a monolateral fixator. Bone formation was assessed histologically over a 35-day time course. The steady state expression of a broad family of angiogenesis-as...

BACKGROUND The aim of this study was to evaluate the efficacy, safety profile, and complications associated with mandibular distraction osteogenesis performed in infants weighing less than 4 kg with Robin sequence. METHODS An 11-year retrospective review of all infants (younger than 6 months) with mandibular distraction osteogenesis-treated Robin sequence was performed. Patients weighing less...

PURPOSE: Although numerous publications have described distraction osteogenesis (DO) for craniosynostosis, methods of reporting quantitative results have been inconsistent. Therefore, the efficacy of anterior DO and posterior DO in regards to volume change is not well established. We report a metric that relates volume change to distraction length and our analysis of ICV change by distraction o...

normal 0 false false false en-us x-none ar-sa microsoftinternetexplorer4 background : distraction osteogenesis is an established option for reconstruction of amputated fingers. in contrast to the primary method of distraction osteogenesis, using kirschner wire (k-wire) as an internal fixator is not common today. this study was conducted to evaluate distraction osteogenesis with and without k-wi...

PURPOSE: Although numerous publications have described distraction osteogenesis (DO) for craniosynostosis, methods of reporting quantitative results have been inconsistent. Therefore, the efficacy of anterior DO and posterior DO in regards to volume change is not well established. We report a metric that relates volume change to distraction length and our analysis of ICV change by distraction o...

Delayed bone healing during distraction osteogenesis negatively affects clinical outcome. In addition to autologous bone grafting, several mechanical, chemical, biologic, and external treatment modalities may be employed to promote bone growth during distraction osteogenesis in the pediatric patient. Mechanical approaches include compressive loading of the distraction regenerate, increased freq...

This study evaluated bone distracted in rabbit mandibles at different intervals and with different daily rates of distraction histologically with the goal of attaining a universally accepted distraction protocol. Osteogenesis was investigated in mandibles distracted at different rates in 24 New Zealand rabbits using a custom-made submerged distractor. Distraction was started on the third postop...

Goldenhar syndrome is a well-known condition featuring the following triad of anomalies: ocular abnormalities, microtia and vertebral anomalies. This syndrome involves structures arising from the first and second branchial arches. Craniofacial anomalies, including mandibular, zygomatic and/or maxillary hypoplasias are found in 50% of patients with Goldenhar syndrome. Patients with this syndrome...

Distraction osteogenesis is a novel method for neo-tissue generation which involves development of both hard and soft tissue under applied force in certain direction. The major advantage of this procedure is diminishing reliability on grafting for reconstruction hence lack of donor site morbidity. Myriad of applications of distraction osteogenesis are present in maxillofacial surgery field whic...

conclusions callus distraction is an effective and reliable method for lengthening short phalangeal, metacarpal, and metatarsal bones. it also preserves periosteal tissue. our distractor is reliable, cheap, lightweight, user friendly, and highly effective for callotasis. background this study was performed to evaluate the results of finger lengthening following traumatic amputation or congenita...