The duplication of genetic information (DNA replication) is central to life. Numerous control mechanisms ensure the exact course process during each cell division. Disturbances DNA replication have severe consequences for affected cell, and current models link them cancer development. One most accurate methods studying labelling newly synthesised molecules with halogenated nucleotides, followed...

continuous labelling of callus with h-thymidine results in intermittent peaks of h-dna per chloroplast, showing synchrony of division. the increase in h-dna could be due to several replication rounds, and the drop to successive plastid divisions without intervening dna synthesis. the level of dna-binding proteins in the chloroplast parallels the peaks of plastidal dna synthesis; such proteins c...