This study presents a mission management technique that is key component of underwater docking system used to expand the operating range autonomous vehicle (AUV). We analyzed scenario and AUV environment, defining feasible initial area (FIA) level, event global path (GP) command improve rate success safety. Non-holonomic constraints, mounted sensor characteristic, state, behavior were considere...

Nowadays, one of the major goals of the distribution environment is to reduce lead times and inventories. Cross-docking is a logistics technique which removes the storage and picking up the functions of a warehouse. The term cross-docking refers to moving products directly from incoming to outgoing trailers with little or no storage in between. According to the recent related papers, the truck ...

In this study, a new molecular docking method is presented to improve the docking accuracy. We introduce to docking design a concept of residue groups based on induced-fit and use K Score (a kind of PMF scoring function) to score the docking position. Genetic algorithm with the multi-population evolution and entropy-based searching technique with narrowing down space is used to solve the optimi...

► We describe a new technique for robotic infrarenal para-aortic lymphadenectomy. ► This technique includes the new robotic trocar insertion sites. ► We perform the complete lymphadenectomy with a single docking procedure. ► This technique is feasible for complete lymphadenectomy in endometrial staging.

introduction:  stereotactic  radiosurgery  is  a  technique  for  the  treatment  of  intracranial  lesions  with  highly  collimated  x-ray  beam.  linac-based  radiosurgery  is  currently  performed  by  two  techniques:  couch or pedestal mounted. in the first technique, a device is required to affix patient's head to a couch  and  moreover  to  translate  it  accurately.  structure  of...

Docking is a computational technique that samples conformations of small molecules in protein binding sites; scoring functions are used to assess which of these conformations best complements the protein binding site. An evaluation of 10 docking programs and 37 scoring functions was conducted against eight proteins of seven protein types for three tasks: binding mode prediction, virtual screeni...

We have earlier reported the MOLSDOCK technique to perform rigid receptor/flexible ligand docking. The method uses the MOLS method, developed in our laboratory. In this paper we report iMOLSDOCK, the 'flexible receptor' extension we have carried out to the algorithm MOLSDOCK. iMOLSDOCK uses mutually orthogonal Latin squares (MOLS) to sample the conformation and the docking pose of the ligand an...

Docking is possibly the most widely used technique in structure-based drug design. It is recognized as extremely useful to guide the development of active molecules as well as in virtual screening to identify new leads. But docking is also notoriously imperfect and many aspects need to improve. In this talk I will present our work on two different sources of errors in the docking predictions: p...

Protein-ligand docking is an essential technique in computer-aided drug design. While generally available docking programs work well for most drug classes, carbohydrates and carbohydrate-like compounds are often problematic for docking. We discuss the peculiarities of protein-carbohydrate interactions and their impact on protein-carbohydrate docking and review the state of the art in docking of...