PURPOSE The purpose of this study was to assess the relationship between donor factors and 5-year corneal graft survival in the Cornea Donor Study. METHODS Donor corneas met criteria established by the Eye Bank Association of America, had an endothelial cell density of 2300 to 3300/mm, and were determined to be of good to excellent quality by the eye banks. Donor corneas were assigned using a...

In brain-dead donor resuscitation, hydroxyethyl starch (HES) use has been associated with presence of osmotic-nephrosis-like lesions in kidney transplant recipients. Our aim was to determine whether the presence of HES in protocol renal graft biopsies at three months (M3) after transplantation is associated with renal graft quality. According to the HES administered to the donor during the proc...

PURPOSE To validate tissue quality parameters for donor corneas designated for emergency grafting for corneal graft survival. METHODS In a longitudinal cohort follow-up study, 131 emergency penetrating grafts were studied. Grafts were performed with a pool of organ-cultured donor corneas designated for emergency grafting and prepared for immediate use with all safety tests performed. Assignat...

from 1986 to 1996, 1020 renal transplants were performed at our center. the purposes of this study were. 1) to evaluate the patient and graft survival rates and 2) to see if some donors and recipient characteristics such as age, sex and relationship had any effects on graft survivals. 571 transplants were from living related donors (lrd) and 446 from living unrelated donors (lud). 65.9% of reci...

conclusions we found acceptable short-term survival in both groups; however, living donor recipients continue to have better long-term patient and graft survival rates. results although there were no significant differences in one-year survival rates of patient and graft between study groups, three-years survival rates of patient and graft were significantly longer in living donor kidney transp...

Background: Delayed graft function is a main complication after deceased donor kidney transplantation that adversely affects graft outcome. Difficulties in prediction and early detection of delayed graft function have hindered the ability to perform proper therapeutic interventions. We investigated whether measuring urinary interleukin 18 and neutrophi...

BACKGROUND Full-thickness skin graft (FTSG) is a very versatile tool regularly used in small sizes. With the established knowledge of the graft take through the margins as well as wound bed, we extended the use of the FTSG for reconstruction of large-sized defects with satisfactory results.  METHODS We presented our experience in wound reconstruction using FTSG in 28 patients. We select...

OBJECTIVE To determine whether graft survival over a 5-year follow-up period using corneal tissue from donors older than 65 is similar to graft survival using corneas from younger donors. DESIGN Multicenter prospective, double-masked, controlled clinical trial. PARTICIPANTS One thousand ninety subjects undergoing corneal transplantation for a moderate-risk condition (principally Fuchs' dyst...

BACKGROUND Autologous iliac crest graft has long been the gold standard graft material used in cervical fusion. However its harvest has significant associated morbidity, including protracted postoperative pain scores at the harvest site. Thus its continued practice warrants scrutiny, particularly now that alternatives are available. Our aims were to assess incidence and nature of complications ...

Assessment of deceased-donor organ quality is integral to transplant allocation practices, but tools to more precisely measure donor kidney injury and better predict outcomes are needed. In this study, we assessed associations between injury biomarkers in deceased-donor urine and the following outcomes: donor AKI (stage 2 or greater), recipient delayed graft function (defined as dialysis in fir...