There is a wide perception that the paediatric population has been badly served by pharmaceutical companies, drug regulators and governmental funding bodies, in that too little resource has been committed to developing effective and safe medicines for children, and in particular defining the right dose(s) for appropriate paediatric populations (see for example reference [1]). Paediatricians, cl...

The process of estimation of dose at a target organ from the measurements of environmental concentration of potentially hazardous agents is theoretically examined. The analysis of the estimation process suggests that the design of any study which aims to find the health effects of an agent or to construct a dose-response relationship from environmental measurements must be fully scrutinized to ...

Epidemiology and public health research relating to solar ultraviolet (UV) exposure usually relies on dosimetry measure UV doses received by individuals. However, measurement errors affect each unknown amounts, complicating the analysis of such measurements their relationship underlying population associated outcomes. This paper presents a new approach estimate without use dosimeters. By combin...

Introduction: The Diagnostic reference levels (DRLs) play a critical role in the optimization of radiation dose especially, in some conditions like pediatrics. They are useful indicators by which the radiologists can be aware of delivered excess radiation doses to the patients, and take corrective actions if necessary. In order to meet some requirements for establishing the nat...