PURPOSE Radiotherapy of solid tumors has been performed with various fractionation regimens such as multi- and hypofractionations. However, the ability to optimize the fractionation regimen considering the physical dose distribution remains insufficient. This study aims to optimize the fractionation regimen, in which the authors propose a graphical method for selecting the optimal number of fra...

BED model (Biological Effective Dose) for Hyperfractionation TPO was optimized with Pareto-Multiobjective Genetic Algorithms (GA) software. Secondly, the NEffective (Effective Tumor Population Clonogens Number) optimization breast cancer clonogens parameters determination in (Treatment Planning Optimization) is carried out 3D Graphical and Interior Optimization methods. GA Results comprise imag...

PURPOSE Lung cancer radiotherapy treatments employ a wide variety of fractionation protocols. The choice among protocols mostly depends on the size of the target volume (GTV or ITV) and the volume of normal tissue receiving a critical dose. Rigorous mathematical criteria for normal tissue (NT) dose distributions were derived to determine the type of dose per fraction schedule that maximizes lin...

BED model (Biological Effective Dose) for Head and Neck tumors Hyperfractionation TPO was optimizedwith Pareto-Multiobjective (PMO) Genetic Algorithms (GA) software. Artificial Intelligence (AI) with GA is applied on Radiotherapy Treatment Planning Optimization (TPO). Secondly, the review of NEffective (Effective Tumor Population Clonogens Number) optimization breast cancer clonogens parameters...

PURPOSE The paper considers the fractionation problem in intensity modulated proton therapy (IMPT). Conventionally, IMPT fields are optimized independently of the fractionation scheme. In this work, we discuss the simultaneous optimization of fractionation scheme and pencil beam intensities. METHODS This is performed by allowing for distinct pencil beam intensities in each fraction, which are...

A destoner fractionation process was used to separate distillers dried grains with solubles (DDGS) into streams with various compositions. Results showed that destoner fractionation was somewhat efficient and effective. Runs with 8° angle and 27.5 percent air flow resulted in the highest value of protein and oil, which the light fraction had 28.15% protein, 10.50% oil, while the heavy fraction...