OBJECTIVES This study examines cardiovascular (CV) effects of guanfacine immediate-release (GUAN-IR), dexmethylphenidate extended-release (DMPH), and their combination (COMB) during acute and long-term treatment of youth with attention-deficit/hyperactivity disorder. METHODS Two hundred seven participants aged 7-14 years enrolled in an 8-week double-blind randomized trial of GUAN-IR (1-3 mill...

We have reported previously that the cationic comb-type copolymer, PLL-g-Dex, accelerated DNA strand exchange reaction while stabilizing DNA duplexes. In this research, we studied the effects of PLL-g-Dex on a DNA-fueled nanomachine. The copolymer enabled rapid and secure operations of the DNA nanomachine which utilized the structural transition between intramolecular G-quadruplex and intermole...

According to the latest phylogenetic and cytogenetic results, Larnax and Deprea should be merged in order to form a natural group. Consequently, we propose 32 combinations of Larnax species names under Deprea: Depreaabra-patriciae (S.Leiva & Barboza) S.Leiva & Deanna, comb. nov., Depreaaltomayoensis (S.Leiva & Quip.) Barboza & Deanna, comb. nov., Depreaandersonii (N.W.Sawyer) Deanna & S.Leiva, ...

This paper proposes a new method for the pitch detection of a duet song for transcription. The previous pitch detection methods that are considered most for musical instrument sounds but few for sung songs are based on the extraction of the pitch frequencies. But the extraction of the pitches is difficult since the musical sound has many harmonic components. The principle of our method is the e...

Receptor protein tyrosine phosphatases (RPTPs) are important for growth-cone migration [1-5], but their specific roles have yet to be defined. Previously, we showed that the growth cones of the Comb cell, an embryonic cell in the leech, express high levels of an RPTP called HmLAR2 [6,7]. Here, we report the use of RNA interference (RNAi) to block expression of HmLAR2 in individual Comb cells in...

Systematic investigations and phylogenetic analyses of the Blakeeae (Melastomataceae) have indicated that Topobea should be synonymized under Blakea, and Huilaea under Chalybea. Presented here is a detailed description of the Blakeeae, a key to its two accepted genera, and a listing of 62 new combinations, including 3 new names, necessitated by the transfer of Topobea as follows: Blakea acumina...

The family Celyphidae (Diptera, Lauxanioidea) is verified as part of the New World fauna, with a second specimen discovered of a species described from French Guiana in 1844 by P.J.M. Macquart. As this species possesses characteristics that clearly suggest a separate lineage from the Old World celyphids, a new genus is proposed, Atopocelyphusgen. n., with the type species, Celyphus ruficollis M...

Macrostomus ferrugineus (Fabricius, 1805), the type-species of Macrostomus Wiedemann, 1817 and Porphyrochroa palliata (Coquillett, 1902), the type-species of Porphyrochroa Melander, 1927 are redescribed and figured from the types. Both Neotropical genera are considered sister-groups and their synapomorphies are presented. The species belonging to both genera, and those Neotropical species remai...

The formation of unusual multilayered parallel lamellae-in-lamellae in symmetric supramolecular double-comb diblock copolymers is presented. While keeping the concentration of surfactant fixed, the number of internal layers was found to increase with molecular weight M up to 34 for the largest block copolymer. The number of internal structures n was established to scale as M0.67 and therefore e...

The generic classification of the Australian Byrrhinae is revised and the following new genera are described: Notolioon gen. n., Nothochaetes gen. n., Idiothrix gen. n., Akidomorychus gen. n., Brachybyrrhulus gen. n. and Pseudomorychus gen. n. A key is provided for the genera of Australian Byrrhidae. The following new combinations are proposed: Notolioon atronitens (Lea 1920) comb. n., N. bryop...