نتایج جستجو برای: double negative tdnt lymphocyte

تعداد نتایج: 815913  

Journal: :The Journal of Experimental Medicine 1995
C J Guidos C J Williams G E Wu C J Paige J S Danska

Antigen-binding diversity is generated by site-specific V(D)J recombination of the T cell receptor (TCR) and immunoglobulin loci in lymphocyte precursors. Coordinate expression of two structurally distinct recombinase activating genes, RAG-1 and RAG-2, is necessary for activation of site-specific V(D)J recombination. In mice bearing targeted disruptions of either the RAG-1 or RAG-2 genes, T and...

Journal: :Quarterly of Applied Mathematics 2019

Journal: :international journal of data envelopment analysis 0
f. roozbeh r. eslami m. ahadzadeh namin

in this paper, it is assumed that the “decision making units“( ) are consist of positive and negative input and output. firstly, the optimistic and pessimistic models have been suggested by using negative data and then units with most productive scale size are measured in optimistic and pessimistic models. these productive values are compared with double frontiers and hurwicz’s criterion to obt...

Journal: :The EMBO journal 2014
Jieun Kim Sung Kyu Lee Yoon Jeon Yehyun Kim Changjin Lee Sung Ho Jeon Jaegal Shim In-Hoo Kim Seokmann Hong Nayoung Kim Ho Lee Rho Hyun Seong

TopBP1 was initially identified as a topoisomerase II-β-binding protein and it plays roles in DNA replication and repair. We found that TopBP1 is expressed at high levels in lymphoid tissues and is essential for early lymphocyte development. Specific abrogation of TopBP1 expression resulted in transitional blocks during early lymphocyte development. These defects were, in major part, due to abe...

Journal: :Journal of bacteriology 1997
F Fukumori C P Saint

A 9,233-bp HindIII fragment of the aromatic amine catabolic plasmid pTDN1, isolated from a derivative of Pseudomonas putida mt-2 (UCC22), confers the ability to degrade aniline on P. putida KT2442. The fragment encodes six open reading frames which are arranged in the same direction. Their 5' upstream region is part of the direct-repeat sequence of pTDN1. Nucleotide sequence of 1.8 kb of the re...

2005
Jiing-Dwan Lee Jeng-Fan Lo He Zhou Colleen Fearns Ralph A. Reisfeld Young Yang

Journal: :Physical review. E, Statistical, nonlinear, and soft matter physics 2004
Jensen Li C T Chan

We show here the existence of acoustic metamaterial, in which both the effective density and bulk modulus are simultaneously negative, in the true and strict sense of an effective medium. Our double-negative acoustic system is an acoustic analogue of Veselago's medium in electromagnetism, and shares many unique consequences, such as negative refractive index. The double negativity in acoustics ...

2011
IN Lavrentieva SR Rodionovskaya IN Tsymbal MA Maschan TA Visotskaya

Background Autoimmune lymphoproliferative syndrome (ALPS) a disease which is based on primary violations lymphocyte apoptosis caused by various molecular defects: mutation in the proapoptotic receptor Fas (la ALPS type) or its ligand FasL (Ib type), a mutation in the gene caspase10 (type II), or an unidentified defect in the signaling pathway of Fas-receptor (III type). The typical clinical pic...

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