To the Editor: Over recent years, invasive hypertension treatments have led to a new clinical condition, called device-resistant hypertension (DRH).1 DRH is defined as blood pressure (BP) >140/90 mm Hg, with at least 3 antihypertensives at maximal doses, including a diuretic,2 without BP decrease after the invasive treatments. These patients are not infrequent and are obliged to visit several h...

A carcinogen-resistant inbred strain DRH/Sea has been developed from the Crj:Donryu strain. The rats had a very low incidence of liver tumors when they were fed diets containing a hepatocarcinogen such as 3'-methyl-4-dimethylamino-azobenzene (3'-Me-DAB). Despite using 3'-Me-DAB during the stage of selection, the DRH/Sea rats developed normally, reproduced and did not have any spontaneous tumor ...

Dicer ribonucleases of plants and invertebrate animals including Caenorhabditis elegans recognize and process a viral RNA trigger into virus-derived small interfering RNAs (siRNAs) to guide specific viral immunity by Argonaute-dependent RNA interference (RNAi). C. elegans also encodes three Dicer-related helicase (drh) genes closely related to the RIG-I-like RNA helicase receptors which initiat...

A. L. Miller National Institute for Occupational Safety and Health/ Spokane Research Lab, Spokane, WA 99207, USA Abstract A hygroscopicity tandem differential mobility analyzer (HTDMA) technique is used to determine size-effect of nanoparticles (NaCl, (NH4)2 SO4, KCl, NH4NO3, MgCl2, CaCl2) on their hygro­ scopic properties (deliquescence relative humidity (DRH) and hygroscopic growth factor (GF...

To develop a simple and sensitive method for the simultaneous estimation of drotaverine HCL (DRH) and aceclofenac (AF) using RP-HPLC. The HPLC separation was achieved on a thermo column (250 mm × 4.6 mm, 5μ) with an isocratic mixture of acetonitrile and 5 mM of ammonium acetate in the ratio of 65:35, pH adjusted to 4.5 at a flow rate of 1.0 ml/min and the detection at 285nm. The method was vali...

Let H be a pseudovariety of groups and DRH be the pseudovariety containing all finite semigroups whose regular R-classes belong to H. We study the relationship between reducibility of H and of DRH with respect to several particular classes of systems of equations. The classes of systems considered (of pointlike, idempotent pointlike and graph equations) are known to play a role in decidability ...

The consequences of developmental exposure to methylmercury on behavior in aged animals were investigated. Methylmercury exposure was arranged by placing 0, 0.5 or 6.4 ppm Hg in the drinking water of female rats at least 4 weeks before mating and continuing until post-natal (PN) day 16. Brain Hg concentrations in cohorts of low- and high-dose offspring were 0.5 and 9.1 ppm at birth and 0.04 and...

Instance Search (INS) is a fundamental problem for many applications, while it is more challenging comparing to traditional image search since the relevancy is defined at the instance level. Existing works have demonstrated the success of many complex ensemble systems that are typically conducted by firstly generating object proposals, and then extracting handcrafted and/or CNN features of each...

1. Drug related hospital admissions: more attention is needed for interventions with patients 57 Hallas et al. from the Department of Clinical Pharmacology at the University of Odense (Denmark) investigated drug related hospital admissions (DRH) in sub-specialities of internal medicine. I have discussed earlier in "Safety & Risk in Practice" an intervention study by the Odense DRH survey group ...