detection of adverse drug reactions (adrs) in hospitals provides an important measure of the burden of drug related morbidity on the healthcare system. spontaneous reporting of adrs is scare and several obstacles to such reporting have been identified formerly. this study aimed to determine the role of clinical pharmacy residents in adr reporting within a hospital setting.clinical pharmacy resi...

background pharmacovigilance (pv) data are crucial for ensuring safety and effectiveness of medicines after drugs have been granted marketing approval. this paper describes the pv systems of india, uganda and south africa based on literature and key informant (ki) interviews and compares them with the world health organization’s (who’s) minimum pv requirements for a functional national pv syste...

to inform healthcare professionals of a rare serious reaction leading to leg amputation following intramuscular injection of iron dextran and report comments for preventing such reactions.a case of leg amputation following intramuscular injection of iron dextran reported to iranian pharmacovigilance center was reviewed. patient and reaction data was collected by assessing the reported yellow ca...

user-generated medical messages on internet contain extensive information related to adverse drug reactions (adrs) and are known as valuable resources for post-marketing drug surveillance. the aim of this study was to find an effective method to identify messages related to adrs automatically from online user reviews.we conducted experiments on online user reviews using different feature set an...

background: listeria monocytogenes is one of the most important food-borne bacteria causing septicemia, meningitis and encephalitis in humans. the objective of this study was to evaluate the occurrence and antibiotic resistance of the bacterium in retail minced beef in ahvaz, south-west of iran. methods: in this survey, 150 samples of minced beef were randomly obtained from retail butcheries in...

magnetic resonance imaging (mri) contrast agents most commonly agents used in diagnosing different diseases. several agents have been ever introduced with different peculiar characteristics. they vary in potency, adverse reaction and other specification, so it is important to select the proper agent in different situations. we conducted a systematic literature search in medline/pubmed, web of s...

a-10-year-old girl was referred to our department for multiple hyperpigmented plaques. one  week  previously,  she  had  been  given  one  suppository  of  acetylsalicylic acid  – phenobarbital for fever. twelve hours after the drug intake the child developed pruritic red plaques on the left thigh. six weeks after resolution of the acute reaction, patch tests were performed separately, with phe...