background: antibiotics can be life saving if they are used correctly, and can have unwanted side effects specially resistance with incorrect use. unfortunately in fear of no response, physicians use broad spectrum antibiotics meticulously. in this drug utilization evaluation (due), improper use of vancomycin and five broad-spectrum antibiotics are studied to find faults and solution for this p...

background : since albumin imposes a relatively high cost to a healthcare system, drug use evaluation for this drug is much more important. this study wants to evaluate pattern of albumin use in a large university affiliated hospital in tehran, iran. methods : a concurrent, cross-sectional study was performed in “shaheed rajaei” cardiovascular, medical and research center. all inpatient adults ...

background: drug utilization evaluation (due) studies are designed to evaluate and improve the rational use of medications. dues have focused on drugs used in high risk patients such as critically ill cases in this study. carbapenems are beta-lactam type antibiotics with broad-spectrum of activity which cover gram-positive, gram-negative and anaerobic bacteria. the heavy use of carbapenems (imi...

OBJECTIVE To determine the incidence of clinically relevant potential drug-drug interactions (DDIs) in a large population of ambulatory patients utilizing a computerized, retrospective drug utilization review (DUR) program followed by clinical pharmacist audit. METHODS The drug claims database included approximately 2.9 million patients with more than 30 million prescriptions dispensed in the...

BACKGROUND Drug utilization review (DUR) programs are being conducted in Canadian hospitals with the aim of improving the appropriateness of prescriptions. However, there is little evidence of their effectiveness. The objective of this study was to assess the impact of both a retrospective and a concurrent DUR programs on the quality of in-hospital prescribing. METHODS We conducted an interru...

OBJECTIVES The drug utilization review (DUR) system, which checks any conflict event of medications, contributes to improve patient safety. One of the important barriers in its adoption is doctors' resistance. This study aimed to analyze the impacts of doctors' resistance on the success of the DUR system. METHODS This study adopted an augmented the DeLone and McLean Information System (D&M IS...

background: granulocyte colony stimulating factors (gcsf) are high cost agents commonly recommended for primary and secondary prophylaxis of chemotherapy-induced neutropenia and febrile neutropenia. gcsfs have been shown to be beneficial in some patient subgroups, although they are probably overused in clinical settings. the american society of clinical oncology (asco) guidelines summarize curr...

BACKGROUND The Omnibus Budget Reconciliation Act of 1990 offered the promise that prospective drug utilization review (pDUR) systems would improve the quality of drug prescribing and patient drug use. There is little evidence that this promise has been fulfilled. To the contrary, there is growing evidence that suboptimal use of drugs (in terms of preventable drug-related morbidity) is at least ...

OBJECTIVES This paper proposes new alert override reason codes that are improvements on existing Drug Utilization Review (DUR) codes based on an analysis of DUR alert override cases in a tertiary medical institution. METHODS Data were obtained from a tertiary teaching hospital covering the period from April 1, 2012 to January 15, 2013. We analyzed cases in which doctors had used the 11 overla...