as analyte concentrations increased, within-and between-day imprecision decreased. The CVs of these samples, when assay dilution was accounted for, were consistent with the low (ng/L) LOQ estimated for each SMIA. Highly sensitive and precise SMIAs with excellent recoveries for several other analytes were also developed (Table 1 and see Fig. S1C in the online Data Supplement). All LODs were Ͻ1 n...

In this work we present a novel treatment planning technique called interactive dose shaping (IDS) to be employed for the optimization of intensity modulated radiation therapy (IMRT). IDS does not rely on a Newton-based optimization algorithm which is driven by an objective function formed of dose volume constraints on pre-segmented volumes of interest (VOIs). Our new planning technique allows ...

BACKGROUND Antibodies to microbes, or to autoantigens, are important markers of disease. Antibody detection (serology) can reveal both past and recent infections. There is a great need for development of rational ways of detecting and quantifying antibodies, both for humans and animals. Traditionally, serology using synthetic antigens covers linear epitopes using up to 30 amino acid peptides. ...

As a new technology in the field of remote sensing, hyperspectral sensing has been widely used land classification, mineral exploration, environmental monitoring, and other areas. In recent years, deep learning achieved outstanding results image classification tasks. However, problems such as low accuracy for small sample classes unbalanced datasets lack robustness models usually lead to unstab...