Proteins of the Hha/YmoA family co-regulate with H-NS the expression of horizontally acquired genes in Enterobacteria. Systematic mutations of conserved acidic residues in Hha have allowed the identification of D48 as an essential residue for H-NS binding and the involvement of E25. Mutations of these residues resulted in deregulation of sensitive genes in vivo. D48 is only partially solvent ac...

BACKGROUND AND PURPOSE We have previously shown that 17beta-estradiol reduces infarction volume in female rats. The present study determined whether single injection or chronic implantation of estrogen confers neuroprotection in male animals with middle cerebral artery occlusion (MCAO) and whether there is an interaction with endogenous testosterone. METHODS Male Wistar rats were treated with...

Electrification is considered an optimal long-term solution for the decarbonization of transport sector. However, in medium period, propulsion systems will continue to dominate urban mobility, thus requiring shift from fossil fuels toward low carbon fuels. In this regard, request EU achieve neutrality by 2050 encouraging use innovative and powertrains. Alcohols such as ethanol methanol are part...

The following articles are being highlighted as part of Circulation: Cardiovascular Imaging’s Topic Review. This series summarizes the most important articles, as selected by the editors, that have published in the Circulation portfolio. The studies included in this article represent the most significant research in the area of structural heart disease, cardiac function, aortic disease, and mol...

Previous reports indicate that mutations within the Autographa californica nucleopolyhedrosis virus FP25K gene (open reading frame 61) significantly reduce incorporation of enveloped nucleocapsids into viral occlusions. We report that FP25K is a nucleocapsid protein of both the budded virus (BV) and occluded virus (ODV), and we describe the effects of two FP25K mutations (480-1 [N-terminal trun...

The following articles are being highlighted as part of Circulation: Cardiovascular Imaging’s Topic Review. This series summarizes the most important articles, as selected by the editors, that have published in the Circulation portfolio. The studies included in this article represent the most significant research in the area of structural heart disease, cardiac function, aortic disease, and mol...

Department of Obstetrics and Gynecology, Hadassah Medical Center, Jerusalem, Israel Clinical Research Center, Massachusetts Institute of Technology, E17-445 Cambridge, MA 02139, USA Clinical Research Center, Massachusetts Institute of Technology, E25-604, Cambridge, MA 02139, USA Robertson Centre for Biostatisics, University of Glasgow, Glasgow, Scotland, UK Department of Anatomy and Neurobiolo...

The following articles are being highlighted as part of Circulation: Cardiovascular Imaging’s Topic Review. This series summarizes the most important articles, as selected by the editors, that have published in the Circulation portfolio. The studies included in this article represent the most significant research in the area of structural heart disease, cardiac function, aortic disease, and mol...